Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ALDH1A1 | contributors: mct/npt - updated : 29-11-2023 |
HGNC name | aldehyde dehydrogenase 1 family, member A1 |
HGNC id | 402 |
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Location | 9q21.13 Physical location : 75.515.587 - 75.567.969 |
Synonym name | |
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Synonym symbol(s) | ALDH1, PUMB1, RALDH1, ALDH1A1-PENDING, ALDC, ALDH-E1, ALDH11, MGC2318, ALHDII, HEL-9, HEL-S-53e, HEL12 |
EC.number | 1.2.1.36,1.2.1.3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 52.38 kb 13 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
tissue |
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cells |
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cell lineage | in adult stem cells isolated from bone marrow, brain, breast and possibly other tissues |
cell lines
fluid/secretion
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at STAGE |
physiological period | embryo |
Text | |
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PROTEIN |
PHYSICAL PROPERTIES | globular | |
STRUCTURE |
motifs/domains
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mono polymer | homomer , tetramer |
HOMOLOGY |
intraspecies | paralog to ALDH1A3 |
paralog to ALDH1A2 | |
homolog to ALDH1B1 |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | drug |
signaling |
detoxication of anticancer drugs |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, nucleotide, |
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protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to development of alcohol and other substance use disorders |
Variant & Polymorphism other | |
Candidate gene | ||
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Marker
Therapy target
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ANIMAL & CELL MODELS |
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