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Symbol SYF2 contributors: npt - updated : 21-04-2005
HGNC name SYF2 homolog, RNA splicing factor (S. cerevisiae)
HGNC id 19824
Location 1p36.11      Physical location : 25.548.766 - 25.559.013
Synonym name
  • GCIP-interacting protein p29
  • CCNDBP1 interactor
  • pre-mRNA-splicing factor SYF2
  • Synonym symbol(s) P29, CBPIN, DKFZp564O2082, NTC31, GCIPIP
    DNA
    TYPE functioning gene
    STRUCTURE 10.00 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 1372 29 243 - Chang (00)
    the longest isoform
    - splicing 1247 - 201 - Chang (00)
    lacks an in-frame exon in the coding region, resulting in an isoform lacking an internal segment and the two BNLS, compared to isoform 1
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two BNLS (bipartite nuclear localization signal)
  • HOMOLOGY
    Homologene
    FAMILY
  • SYF2 family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be involved in cell cycle regulation at the G1/S transition, via its interaction with CCNDBP1
  • CELLULAR PROCESS cell cycle, progression
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
  • interacting with CCNDBP1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS