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FLASH GENE
Symbol PYGB contributors: - updated : 27-01-2007
HGNC name phosphorylase, glycogen; brain
HGNC id 9723
Location 20p11.2      Physical location : 25.228.705 - 25.278.647
Synonym name
  • brain glycogen phosphorylase
    • Synonym symbol(s) MGC9213
    EC.number 2.4.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 49.00 kb     20 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
    Nervousbrain    
     nerve   highly
    Skin/Tegumentskin   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY glycogen phosphorylase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION catalyzes the rate-determining step in glycogen degradation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
    pyridoxal phosphate
    protein
    cell & other
    REGULATION
    activated by by AMP
    inhibited by ATP, ADP, and glucose-6-phosphate
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS