Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | DHX8 | contributors: mct - updated : 27-02-2020 |
HGNC name | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
HGNC id | 2749 |
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Location | 17q21.31 Physical location : 41.561.333 - 41.601.680 |
Synonym name | |
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Synonym symbol(s) | PRP22, HRH1, DDX8, C6C1, Dhr2, PRPF22 |
EC.number | 3.6.4.13 |
DNA |
TYPE | functioning gene |
STRUCTURE | 60.93 kb 23 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
regionally located | in a region duplicated on 16p |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | ortholog to yeast S.cerevisiae Prp22 |
homolog to murine Ddx8 | |
homolog to Drosophila CG8241 | |
homolog to C.elegans mog-5 |
Homologene |
FAMILY | DEAD/H box family, DEAH subfamily |
CATEGORY | enzyme , RNA associated , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria | |
intracellular,nucleus,nucleoplasm,nuclear bodies | |
text | transport to nucleus dependent on active RNA POL II transcription |
basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, RNA splicing |
PHYSIOLOGICAL PROCESS | cellular trafficking transport |
text | nuclear export of spliced mRNA |
PATHWAY |
metabolism |
signaling |
a component | spliceosome complex |
INTERACTION |
DNA |
RNA | binding |
small molecule | nucleotide, |
ATP |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
ANIMAL & CELL MODELS |