Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CYBA | contributors: npt/ - updated : 07-05-2007 |
HGNC name | cytochrome b-245, alpha polypeptide |
HGNC id | 2577 |
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Corresponding disease |
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Location | 16q24.3 Physical location : 88.709.697 - 88.717.457 | ||
Synonym name | |||
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Synonym symbol(s) | p22-PHOX |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | arranged in tandem |
STRUCTURE | 7.76 kb 6 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | enzyme , tumor suppressor |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,mitochondria | |
intracellular,cytoplasm,organelle,membrane |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | energetic |
signaling |
superoxide metabolism |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule | metal binding, cofactor, |
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protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | CYBA |
related resource | Autosomal recessive chronic granulomatous disease (CGD) deficiency of p22phox CYBAbase |
Other morbid association(s) |
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Susceptibility |
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Variant & Polymorphism SNP | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |