Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TAF1A | contributors: mct - updated : 17-06-2020 |
HGNC name | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
HGNC id | 11532 |
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Corresponding disease |
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Location | 1q41 Physical location : 222.731.665 - 222.763.255 | ||
Synonym name | |||
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Synonym symbol(s) | TAFI48, SL1, TAF(I)48, MGC:17061, RAFI48, SL1 |
DNA |
TYPE | functioning gene |
STRUCTURE | 32.19 kb 10 Exon(s) |
Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | fetal |
Text | fetal tissues |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to murine Taf1a |
Homologene |
FAMILY |
CATEGORY | DNA associated , transcription factor |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,cytoskeleton,microtubule | |
intracellular,nucleus,nucleoplasm |
CELLULAR PROCESS | nucleotide, transcription |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | component of SL1 (complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I), general transcription factor associated with POLR1, synthesis of 45S RNA precursors |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | CMDTAF1AD |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |