Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

VRK1

contributors: mct/npt/pgu - updated : 09-10-2013

HGNC name	vaccinia related kinase 1
HGNC id	12718

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

PCH1

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   has an impact on the proliferation and survival of cell lines derived from normal or malignant mammary tissue, and reduces their oncogenic and metastatic properties

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target	might be a new target for development of inhibitors of cellular proliferation

ANIMAL & CELL MODELS

mice deficient in the serine/threonine protein kinase Vrk1 are infertile due to a progressive loss of spermatogonia