| 1 | BANF1, VRK1
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| Dephosphorylation of barrier-to-autointegration factor by protein phosphatase 4 and its role in cell mitosis.
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| Zhuang X, Semenova E, Maric D, Craigie R.
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| J Biol Chem 289(2):1119-27. doi: 10.1074/jbc.M113.492777. Epub 2013 Nov 21.
2014
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| 2 | VRK1
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| Molecular genetic analysis of VRK1 in mammary epithelial cells: depletion slows proliferation in vitro and tumor growth and metastasis in vivo.
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| Molitor TP, Traktman P.
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| Oncogenesis 2:e48. doi: 10.1038/oncsis.2013.11.
2013
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| 3 | VRK1, VRK2, VRK3
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| Role of bivalent cations in structural stabilities of new drug targets--vaccinia-related kinases (VRK) from molecular dynamics simulations.
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| Fu T, Ren H, Zhang J, Ren P, Enyedy I, Li G.
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| Curr Pharm Des 19(12):2269-81. Review.
2013
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| 4 | H2AFY, VRK1
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| Macro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphase.
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| Kim W, Chakraborty G, Kim S, Shin J, Park CH, Jeong MW, Bharatham N, Yoon HS, Kim KT.
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| J Biol Chem 287(8):5278-89. doi: 10.1074/jbc.M111.281709. Epub 2011 Dec 22.
2012
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| 5 | HNRNPA1, VRK1
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| HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence.
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| Choi YH, Lim JK, Jeong MW, Kim KT.
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| Nucleic Acids Res 40(17):8499-518. Epub 2012 Jun 26.
2012
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| 6 | VRK1
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| Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage.
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| Sanz-García M, Monsalve DM, Sevilla A, Lazo PA.
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| J Biol Chem 287(28):23757-68. doi: 10.1074/jbc.M112.353102. Epub 2012 May 22.
2012
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| 7 | COIL, VRK1
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| Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications.
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| Sanz-García M, Vázquez-Cedeira M, Kellerman E, Renbaum P, Levy-Lahad E, Lazo PA.
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| J Proteomics 75(2):548-60. doi: 10.1016/j.jprot.2011.08.019. Epub 2011 Sep 3.
2011
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| 8 | VRK1, VRK2
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| Differential inhibitor sensitivity between human kinases VRK1 and VRK2.
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| Vázquez-Cedeira M, Barcia-Sanjurjo I, Sanz-García M, Barcia R, Lazo PA.
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| PLoS One 6(8):e23235. doi: 10.1371/journal.pone.0023235. Epub 2011 Aug 4.
2011
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| 9 | VRK1
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| Roles of VRK1 as a new player in the control of biological processes required for cell division.
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| Valbuena A, Sanz-García M, López-Sánchez I, Vega FM, Lazo PA.
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| Cell Signal 23(8):1267-72. doi: 10.1016/j.cellsig.2011.04.002. Epub 2011 Apr 14. Review.
2011
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| 10 | VRK1
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| NMR solution structure of human vaccinia-related kinase 1 (VRK1) reveals the C-terminal tail essential for its structural stability and autocatalytic activity.
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| Shin J, Chakraborty G, Bharatham N, Kang C, Tochio N, Koshiba S, Kigawa T, Kim W, Kim KT, Yoon HS.
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| J Biol Chem 286(25):22131-8. doi: 10.1074/jbc.M110.200162. Epub 2011 May 3.
2011
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| 11 | VRK1
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| The kinase VRK1 is required for normal meiotic progression in mammalian oogenesis.
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| Schober CS, Aydiner F, Booth CJ, Seli E, Reinke V.
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| Mech Dev 128(3-4):178-90. doi: 10.1016/j.mod.2011.01.004. Epub 2011 Jan 26.
2011
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| 12 | VRK1, VRK2, VRK3
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| NMR solution structure of human vaccinia-related kinase 1 (VRK1) reveals the C-terminal tail essential for its structural stability and autocatalytic activity.
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| Shin J, Chakraborty G, Bharatham N, Kang C, Tochio N, Koshiba S, Kigawa T, Kim W, Kim KT, Yoon HS.
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| J Biol Chem 286(25):22131-8. doi: 10.1074/jbc.M110.200162. Epub 2011 May 3.
2011
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| 13 | VRK1
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| Mice deficient in the serine/threonine protein kinase VRK1 are infertile due to a progressive loss of spermatogonia.
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| Wiebe MS, Nichols RJ, Molitor TP, Lindgren JK, Traktman P.
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| Biol Reprod 82(1):182-93. doi: 10.1095/biolreprod.109.079095. Epub 2009 Aug 19.
2010
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| 14 | PCH1, PCH2A, PCH2B, PCH2C, PCH4, TSEN2, TSEN34, TSEN54, VRK1
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| Spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene.
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| Renbaum P, Kellerman E, Jaron R, Geiger D, Segel R, Lee M, King MC, Levy-Lahad E.
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| Am J Hum Genet 85(2):281-9. Epub 2009 Jul 30.
2009
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| 15 | CCND1, VRK1
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| VRK1 phosphorylates CREB and mediates CCND1 expression.
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| Kang TH, Park DY, Kim W, Kim KT.
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| J Cell Sci 121(Pt 18):3035-41. Epub 2008 Aug 19.
2008
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| 16 | VRK1
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| Human VRK1 is an early response gene and its loss causes a block in cell cycle progression.
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| Valbuena A, López-Sánchez I, Lazo PA.
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| PLoS One 3(2):e1642.
2008
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| 17 | VRK1
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| Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations.
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| Valbuena A, López-Sánchez I, Vega FM, Sevilla A, Sanz-García M, Blanco S, Lazo PA.
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| Arch Biochem Biophys 465(1):219-26. Epub 2007 Jun 14.
2007
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| 18 | VRK1
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| VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.
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| Santos CR, Rodríguez-Pinilla M, Vega FM, Rodríguez-Peralto JL, Blanco S, Sevilla A, Valbuena A, Hernández T, van Wijnen AJ, Li F, de Alava E, Sánchez-Céspedes M, Lazo PA.
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| Mol Cancer Res 4(3):177-85.
2006
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| 19 | VRK1, JUN
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| c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK).
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| Sevilla A, Santos CR, Barcia R, Vega FM, Lazo PA.
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| Oncogene 23(55):8950-8. 2004
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| 20 | VRK1, VRK2, VRK3
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| Characterization of three paralogous members of the Mammalian vaccinia related kinase family.
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| Nichols RJ, Traktman P.
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| J Biol Chem 279(9):7934-46. Epub 2003 Nov 25. 2004
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| 21 | ESRRA, ESRRB, ESRRAP1, VRK1, VRK2
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| Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase.
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| Nezu J, Oku A, Jones MH, Shimane M.
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| Genomics 45(2):327-31 1997
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