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FLASH GENE

Symbol

PER2

contributors: mct/npt - updated : 20-12-2016

HGNC name	period homolog 2 (Drosophila)
HGNC id	8846

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

FASPS

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --other   deregulation in breast cancer not caused by genetic mutations but most probably by methylation of the PER2 promoter

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia
Therapy target

ANIMAL & CELL MODELS

dominant role of PER2 in the positive regulator of (BMAL1) loop