Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | AP1S1 | contributors: mct/npt - updated : 11-10-2017 |
HGNC name | adaptor-related protein complex 1, sigma 1 subunit |
HGNC id | 559 |
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Corresponding disease |
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Location | 7q22.1 Physical location : 100.797.685 - 100.804.556 | ||
Synonym name | |||
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Synonym symbol(s) | AP19, CLAPS1, SIGMA1A, FLJ92436, WUGSC:H_DJ0747G18.2 |
DNA |
TYPE | functioning gene |
STRUCTURE | 6.87 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D7S479 - ASNS - TAC1 - NPTX2 - D8S651 - AP1S1 - SERPINE1 - D7S518 - D7S658 - qter |
Authors | Gene Map (98) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | heteromer , tetramer |
HOMOLOGY |
interspecies | ortholog to S cerevisiae,Yap17p |
Homologene |
FAMILY |
CATEGORY | adaptor , transport carrier |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,Golgi | |
intracellular,cytoplasm,cytosolic | |
text | form the AP-1 assembly protein complex located at the Golgi vesicle |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | endocytosis transport , cellular trafficking transport |
PATHWAY |
metabolism |
signaling |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | MEDNIK |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |