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FLASH GENE
Symbol NR6A1 contributors: mct - updated : 18-03-2008
HGNC name nuclear receptor subfamily 6, group A, member 1
HGNC id 7985
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal modulator domain
  • a central bipartite zinc finger
  • a DNA binding domain
  • a C terminal ligand domain
    • HOMOLOGY
    Homologene
    FAMILY
  • nuclear receptor subfamily 6, group A
  • steroid/thyroid receptor superfamily
    • CATEGORY receptor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • germ cell nuclear receptor, potentially involved in spermatogenic maturation
  • required for establishment of the isthmic organizer, thereby regulating the midbrain development
  • playing a central role during differentiation of stem cells by repression of stem cell-specific genes
  • works as a regulator for hypocretin transcription
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with UIMC1
    cell & other
    REGULATION
    Other regulated by UIMC1
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS