| protein
| troponin I ( |
|
lactoferrin, LTF ( |
|
major intrinsic protein of lens fiber MIP26 ( |
|
in endothelial cells, EDF1 bound with CALM1, through its IQ domain sequestering this complex in the cytoplasm of endothelial cells |
|
tubulin binding site on tau protein ( |
|
Smooth muscle calponin, Sm-Calp ( |
|
p68 RNA helicase, p68 ( |
|
CaM-dependent protein kinase I, CaMKI ( |
|
clathrin-coated vesicles, triskelions, and light chains ( |
|
glucocorticoid receptor, GR ( |
|
NR1 subunit ( |
|
IQ motif containing GTPase activating protein 1, IQGAP1 ( |
|
Q motif containing GTPase activating protein 2, IQGAP2 ( |
|
Ric (Drosophila)-like, expressed in neurons, RIN ( |
|
growth associated protein 43, GAP43 ( |
|
caldesmon, CALD1 ( |
|
GRK4alpha ( |
|
Rad and Rad-related GTPases ( |
|
v-ral simian leukemia viral oncogene homolog A (ras related), RAlA ( |
|
A-kinase anchor protein 79 kDa, AKAP79 ( |
|
prooncoprotein EWS ( |
|
alpha1-syntrophin ( |
|
GRK1, GRK2, and GRK5 ( |
|
cyclin-dependent kinase 4, CDK4 and cyclin D1, CCND1 ( |
|
intermediate conductance KCa channel, hIKCa1 ( |
|
synapse-associated protein 102, NE-dlg/SAP102 ( |
|
neurogranin, NRGN ( |
|
adenylyl cyclase type VIII, ACVIII ( |
|
14-3-3 epsilon isoform protein ( |
|
myosin light chain kinase (MLCK), 3'-5'-cyclic nucleotide phosphodiesterase (PDE), plasma membrane (PM) Ca2+-ATPase, Ca2+-CaM dependent protein phosphatase 2B (calcineurin); neuronal nitric oxide synthase, NOS and type II Ca2+-calmodulin dependent protein kinase, CaM kinase II ( |
|
bHLH proteins ( |
|
endothelial differentiation-related factor-1, EDF1 ( |
|
protein kinase C, PKC ( |
|
Zinedin, SG2NA, and striatin ( |
|
protein-tyrosine phosphatase alpha, PTPalpha ( |
|
Myosin VIIA, MYO7A ( |
|
human cardiac titin kinase, hTK ( |
|
CaT-L ( |
|
SK channel ( |
|
mu opioid receptor, MOR ( |
|
K-Ras ( |
|
RAB3B, member RAS oncogene family ( |
|
Estrogen receptor alpha, ERalpha ( |
|
KCNQ2, KCNQ3, or KCNQ5 ( |
|
v-ral simian leukemia viral oncogene homolog B (ras related), RALB ( |
|
protein phosphatase, EF-hand calcium binding domain 1, PPEF1 and protein phosphatase, EF-hand calcium binding domain 2, PPEF2 ( |
|
phosphodiesterase 1A calmodulin-dependent, PDE1A ( |
|
ryanodine receptor 1 (skeletal), RYR1 ( |
|
c-Rel and RelA ( |
|
cyclic nucleotide gated channel alpha 2, CNGA2 and cyclic nucleotide gated channel beta 1, CNGB1 ( |
|
estrogen-related receptor gamma, ERR-gamma ( |
|
transient receptor potential cation channel, subfamily V, member 4, TRPV4 ( |
|
transient receptor potential cation channel, subfamily V, member 1, TRPV1 ( |
|
Fas?, APO-1/CD95 ( |
|
androgen receptor in prostate cancer cells ( |
|
epidermal growth factor receptor, EGFR ( |
|
transglutaminase 2 and huntingtin ( |
|
parathyroid hormone 1 receptor, PTH1R ( |
|
C-terminal domains of adult skeletal (NaV1.4) and cardiac (NaV1.5) muscle NaChs ( |
|
growth factor receptor-bound protein 7, GRB7 ( |
|
PLC-delta1 ( |
|
cyclin-dependent kinase 2, CDK2 ( |
|
CALM1 suppresses SYTL2 transcription in cortical neurons |
|
CALM1 associated with AKAP5 is able to activate anchored PP2B within the same signaling complex |
|
MAPT interacts with CALM1 (the lack of MAPT in neurons changes the subcellular localization of CALM1 and that it correlates with a change in the expression of calbindin) |
|
S100A1 and CALM1 bind to an overlapping domain on the ryanodine receptor type 1 to tune the Ca2+ release process, and thereby regulate skeletal muscle function |
|
CALM1 and S100A1 serve as important regulators of TRPM3, which is known to play an important role in Ca2+ homeostasis |
|
interaction between CALM1 and ARHGEF7 (CALM1 participates in a multi-protein complex involving ARHGEF7 and CBL, which may play a critical role in receptor tyrosine kinase regulation and downstream signaling) |
|
CALM1- activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis |
|
is a known interaction partner of AKAP5 that has been shown to regulate activity of the kinase PKC in a Ca(2+) -dependent manner |
|
CALM1 may act as a structural conduit that links MYBPC3 with Ca(2+) signaling pathways to help coordinate phosphorylation events and synchronize the multiple interactions between MYBPC3, myosin, and actin during the heart muscle contraction |
|
binds directly to RYR2 |
|
interaction of KCNIP3 with the important EF-hand protein, CALM1, and this interaction alters calcineurin (CN) activity |
|
FAS-CALM1 interactions, and CALM1 antagonists greatly inhibit FAS-CALM1 interactions by blocking the FAS-binding site on CALM1 |
|
CALM1 is known to modulate the inactivation kinetics of SCN8A by interacting with its IQ motif |
|
CALM1 binds PPP3CA regulatory domain (RD) and causes a conformational change that removes PPP3CA autoinhibitory domain (AID) from its catalytic site, activating PPP3CA |
|
CALM1 is involved in the Ca(2+)-dependent regulation of TRPV1 via its binding to the TRPV1 C-terminal region |
|
NRGN-mediated enhancement of synaptic strength is due to its ability to target, rather than sequester, CALM1 within dendritic spines |
|
CALM1 and CAMK2A modulate SCNN1A activity by destabilizing the association between the actin cytoskeleton, SCNN1A, and MARCKS, or MARCKSL1 at the apical membrane |
|
CALM1 and S100A1 can concurrently bind to and functionally modulate RYR1 and RYR2, but this does not involve direct competition at the RYR CALM binding site |
|
CALM1 in complex with the first IQ motif of MYO5A functions as an intact calcium sensor |
|
CALM1 does stimulate PI3K lipid kinase activity by binding MARCKS and displacing it from PIP2 headgroups |
|
interaction between CALM1 and GJC1 in cells is strongly dependent on intracellular Ca2+ concentration and can be blocked by the CALM1 inhibitor |
|
|
