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References OMIM Gene GeneReviews HGMD HGNC
last update : 31-10-2012
Symbol CPVT4
Location 14q32.11
Name catecholaminergic polymorphic ventricular tachycardia 4
Corresponding gene CALM1
Main clinical features
  • ventricular arrhythmias, syncope, and sudden death, predominantly in association with physical exercise or stress
  • Genetic determination autosomal dominant
    Function/system disorder cardiovascular
    Type disease
  • defective interaction between RYR2 and calmodulin is part of the pathogenic mechanism for CPVT