Citations for
1CALM1, CALM2, CALM3, LQT14, LQT15, LQT16
A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome.
Limpitikul WB, Dick IE, Tester DJ, Boczek NJ, Limphong P, Yang W, Choi MH, Babich J, DiSilvestre D, Kanter RJ, Tomaselli GF, Ackerman MJ, Yue DT.
Circ Res 120(1):39-48. doi: 10.1161/CIRCRESAHA.116.309283. Epub 2016 Oct 20. 2017
2CALM1, GJC1
Direct visualization of interaction between calmodulin and connexin45.
Zou J, Salarian M, Chen Y, Zhuo Y, Brown NE, Hepler JR, Yang JJ.
Biochem J 474(24):4035-4051. doi: 10.1042/BCJ20170426. 2017
3CALM1, MARCKS
Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module.
Ziemba BP, Swisher GH, Masson G, Burke JE, Williams RL, Falke JJ.
Biochemistry 55(46):6395-6405. 2016
4CALM1, RYR1, RYR2, S100A1
S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine ReceptorˇCalmodulin Complex.
Rebbeck RT, Nitu FR, Rohde D, Most P, Bers DM, Thomas DD, Cornea RL.
J Biol Chem 291(30):15896-907. doi: 10.1074/jbc.M115.713107. Epub 2016 May 19. 2016
5CALM1, MYO5A
Calmodulin in complex with the first IQ motif of myosin-5a functions as an intact calcium sensor.
Shen M, Zhang N, Zheng S, Zhang WB, Zhang HM, Lu Z, Su QP, Sun Y, Ye K, Li XD.
Proc Natl Acad Sci U S A 113(40):E5812-E5820. Epub 2016 Sep 19. 2016
6CALM1, CALM2, CALM3, LQT14, LQT15, LQT16
Novel CALM3 mutations in pediatric long QT syndrome patients support a CALM3-specific calmodulinopathy.
Chaix MA, Koopmann TT, Goyette P, Alikashani A, Latour F, Fatah M, Hamilton RM, Rioux JD.
HeartRhythm Case Rep 2(3):250-254. doi: 10.1016/j.hrcr.2016.02.002. eCollection 2016 May. No abstract available. 2016
7CALM1, CALM2, CALM3, LQT14, LQT15, LQT16
Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome-Associated Calmodulin Missense Variant, E141G.
Boczek NJ, Gomez-Hurtado N, Ye D, Calvert ML, Tester DJ, Kryshtal D, Hwang HS, Johnson CN, Chazin WJ, Loporcaro CG, Shah M, Papez AL, Lau YR, Kanter R, Knollmann BC, Ackerman MJ.
Circ Cardiovasc Genet 9(2):136-146. doi: 10.1161/CIRCGENETICS.115.001323. Epub 2016 Mar 11. 2016
8CALM1, CALM2, LQT14, LQT15
Novel calmodulin mutations associated with congenital long QT syndrome affect calcium current in human cardiomyocytes.
Pipilas DC, Johnson CN, Webster G, Schlaepfer J, Fellmann F, Sekarski N, Wren LM, Ogorodnik KV, Chazin DM, Chazin WJ, Crotti L, Bhuiyan ZA, George AL Jr.
Heart Rhythm 13(10):2012-9. doi: 10.1016/j.hrthm.2016.06.038. Epub 2016 Jul 1. 2016
9CALM1, INP5JJ, S100A1, TRPV1
Ca(2+) binding protein S100A1 competes with calmodulin and PIP2 for binding site on the C-terminus of the TPRV1 receptor.
Grycova L, Holendova B, Lansky Z, Bumba L, Jirku M, Bousova K, Teisinger J.
ACS Chem Neurosci 6(3):386-92. doi: 10.1021/cn500250r. Epub 2014 Dec 31. 2015
10ATP2B2, ATP2B3, CALM1, GAP43, PPP3CA
Regulation of GAP43/calmodulin complex formation via calcineurin-dependent mechanism in differentiated PC12 cells with altered PMCA isoforms composition.
Boczek T, Ferenc B, Lisek M, Zylinska L.
Mol Cell Biochem 407(1-2):251-62. doi: 10.1007/s11010-015-2473-4. 2015
11CALM1, CAMK2A, MARCKS, MARCKSL1, SCNN1A
Calmodulin and CaMKII modulate ENaC activity by regulating the association of MARCKS and the cytoskeleton with the apical membrane.
Alli AA, Bao HF, Liu BC, Yu L, Aldrugh S, Montgomery DS, Ma HP, Eaton DC.
Am J Physiol Renal Physiol 309(5):F456-63. doi: 10.1152/ajprenal.00631.2014. 2015
12CALM1, COBL
The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin.
Hou W, Izadi M, Nemitz S, Haag N, Kessels MM, Qualmann B.
PLoS Biol 13(9):e1002233. doi: 10.1371/journal.pbio.1002233. eCollection 2015. 2015
13CALM1, CALM3
Calm1 signaling pathway is essential for the migration of mouse precerebellar neurons.
Kobayashi H, Saragai S, Naito A, Ichio K, Kawauchi D, Murakami F.
Development 142(2):375-84. doi: 10.1242/dev.112680. Epub 2014 Dec 17. 2015
14CALM1, RYR2
Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure.
Yang Y, Guo T, Oda T, Chakraborty A, Chen L, Uchinoumi H, Knowlton AA, Fruen BR, Cornea RL, Meissner G, Bers DM.
Circ Res 114(2):295-306. doi: 10.1161/CIRCRESAHA.114.302857. Epub 2013 Nov 1. 2014
15CALM1, LQT14
A mutation in CALM1 encoding calmodulin in familial idiopathic ventricular fibrillation in childhood and adolescence.
Marsman RF, Barc J, Beekman L, Alders M, Dooijes D, van den Wijngaard A, Ratbi I, Sefiani A, Bhuiyan ZA, Wilde AA, Bezzina CR.
J Am Coll Cardiol 63(3):259-66. doi: 10.1016/j.jacc.2013.07.091. Epub 2013 Sep 25. 2014
16CALM1, EDF1, NFATC1, PPP3CA
EDF-1 downregulates the CaM/Cn/NFAT signaling pathway during adipogenesis.
López-Victorio CJ, Velez-delValle C, Beltrán-Langarica A, Kuri-Harcuch W.
Biochem Biophys Res Commun 432(1):146-51. doi: 10.1016/j.bbrc.2013.01.069. Epub 2013 Feb 1. 2013
17CALM1, PCP4
The calmodulin regulator protein, PEP-19, sensitizes ATP-induced Ca2+ release.
Wang X, Xiong LW, El Ayadi A, Boehning D, Putkey JA.
J Biol Chem 288(3):2040-8. doi: 10.1074/jbc.M112.411314. Epub 2012 Nov 30. 2013
18CALM1, PPP3CA
The distal helix in the regulatory domain of calcineurin is important for domain stability and enzyme function.
Dunlap TB, Cook EC, Rumi-Masante J, Arvin HG, Lester TE, Creamer TP.
Biochemistry 52(48):8643-51. doi: 10.1021/bi400483a. Epub 2013 Nov 15. 2013
19CALM1, PPP3CA
Structural basis of calcineurin activation by calmodulin.
Ye Q, Feng Y, Yin Y, Faucher F, Currie MA, Rahman MN, Jin J, Li S, Wei Q, Jia Z.
Cell Signal 25(12):2661-7. doi: 10.1016/j.cellsig.2013.08.033. Epub 2013 Sep 7. 2013
20CALM1, SCN8A
Structural basis for the modulation of the neuronal voltage-gated sodium channel NaV1.6 by calmodulin.
Reddy Chichili VP, Xiao Y, Seetharaman J, Cummins TR, Sivaraman J.
Sci Rep 3:2435. doi: 10.1038/srep02435. 2013
21CALM1, CALM2, LQT14, LQT15
Calmodulin mutations associated with recurrent cardiac arrest in infants.
Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL Jr.
Circulation 127(9):1009-17. doi: 10.1161/CIRCULATIONAHA.112.001216. Epub 2013 Feb 6. 2013
22CALM1, CALM2, LQT14, LQT15
Calmodulin mutations associated with recurrent cardiac arrest in infants.
Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL Jr.
Circulation 127(9):1009-17. doi: 10.1161/CIRCULATIONAHA.112.001216. Epub 2013 Feb 6. 2013
23CALM1, CPVT4
Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death.
Nyegaard M, Overgaard MT, Sřndergaard MT, Vranas M, Behr ER, Hildebrandt LL, Lund J, Hedley PL, Camm AJ, Wettrell G, Fosdal I, Christiansen M, Břrglum AD.
Am J Hum Genet 91(4):703-12. doi: 10.1016/j.ajhg.2012.08.015. 2012
24ARHGEF7, CALM1
A novel calmodulin-β-PIX interaction and its implication in receptor tyrosine kinase regulation.
Singh VK, Munro K, Jia Z.
Cell Signal 24(9):1790-6. doi: 10.1016/j.cellsig.2012.05.005. Epub 2012 May 12. 2012
25CALM1, DLG1, GJB1
Characterization of the structure and intermolecular interactions between the connexin 32 carboxyl-terminal domain and the protein partners synapse-associated protein 97 and calmodulin.
Stauch K, Kieken F, Sorgen P.
J Biol Chem 287(33):27771-88. doi: 10.1074/jbc.M112.382572. Epub 2012 Jun 20. 2012
26AURKA, CALM1
Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis.
Plotnikova OV, Nikonova AS, Loskutov YV, Kozyulina PY, Pugacheva EN, Golemis EA.
Mol Biol Cell 23(14):2658-70. doi: 10.1091/mbc.E11-12-1056. Epub 2012 May 23. 2012
27AKAP5, CABP1, CALM1
AKAP79/150 interacts with the neuronal calcium-binding protein caldendrin.
Gorny X, Mikhaylova M, Seeger C, Reddy PP, Reissner C, Schott BH, Helena Danielson U, Kreutz MR, Seidenbecher C.
J Neurochem 122(4):714-26. doi: 10.1111/j.1471-4159.2012.07828.x. Epub 2012 Jul 10. 2012
28CALM1, S100A1, TRPM3
Calmodulin and S100A1 protein interact with N terminus of TRPM3 channel.
Holakovska B, Grycova L, Jirku M, Sulc M, Bumba L, Teisinger J.
J Biol Chem 287(20):16645-55. doi: 10.1074/jbc.M112.350686. Epub 2012 Mar 27. 2012
29CALM1, PPP3CA
Structural basis for activation of calcineurin by calmodulin.
Rumi-Masante J, Rusinga FI, Lester TE, Dunlap TB, Williams TD, Dunker AK, Weis DD, Creamer TP.
J Mol Biol 415(2):307-17. doi: 10.1016/j.jmb.2011.11.008. Epub 2011 Nov 12. 2012
30CALM1, MYBPC3
The motif of human cardiac myosin-binding protein C is required for its Ca2+-dependent interaction with calmodulin.
Lu Y, Kwan AH, Jeffries CM, Guss JM, Trewhella J.
J Biol Chem 287(37):31596-607. doi: 10.1074/jbc.M112.383299. 2012
31CALM1, KCNIP3
The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin function.
Ramachandran PL, Craig TA, Atanasova EA, Cui G, Owen BA, Bergen HR 3rd, Mer G, Kumar R.
J Biol Chem 287(47):39439-48. doi: 10.1074/jbc.M112.398495. Epub 2012 Sep 27. 2012
32CALM1
Calmodulin as a direct detector of Ca2+ signals.
Faas GC, Raghavachari S, Lisman JE, Mody I.
Nat Neurosci. 14(3):301-4 2011
33AKAP5, CALM1
Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex.
Gold MG, Stengel F, Nygren PJ, Weisbrod CR, Bruce JE, Robinson CV, Barford D, Scott JD.
Proc Natl Acad Sci U S A 108(16):6426-31. Epub 2011 Apr 4. 2011
34CALM1, MAPT
Tau regulates the subcellular localization of calmodulin.
Barreda EG, Avila J.
Biochem Biophys Res Commun 408(3):500-4. Epub 2011 Apr 21. 2011
35CALM1, S100A1
S100A1 and calmodulin regulation of ryanodine receptor in striated muscle.
Prosser BL, Hernández-Ochoa EO, Schneider MF.
Cell Calcium 50(4):323-31. doi: 10.1016/j.ceca.2011.06.001. Epub 2011 Jul 23. Review. 2011
36CALM1, RYR1, S100A1
Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1.
Yamaguchi N, Prosser BL, Ghassemi F, Xu L, Pasek DA, Eu JP, Hernández-Ochoa EO, Cannon BR, Wilder PT, Lovering RM, Weber D, Melzer W, Schneider MF, Meissner G.
Am J Physiol Cell Physiol 300(5):C998-C1012. doi: 10.1152/ajpcell.00370.2010. Epub 2011 Feb 2. 2011
37CALM1, KRAS
K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function.
Alvarez-Moya B, López-Alcalá C, Drosten M, Bachs O, Agell N.
Oncogene 29(44):5911-22. Epub 2010 Aug 30. 2010
38CALM1
Site-specific modification of calmodulin Ca˛(+) affinity tunes the skeletal muscle ryanodine receptor activation profile.
Jiang J, Zhou Y, Zou J, Chen Y, Patel P, Yang JJ, Balog EM.
Biochem J 432(1):89-99. 2010
39CALM1, SYTL2
Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.
Pang ZP, Xu W, Cao P, Südhof TC.
J Biol Chem 285(44):33930-9. doi: 10.1074/jbc.M110.150151. Epub 2010 Aug 20. 2010
40CALM1, NRGN, PCP4
PEP-19, an intrinsically disordered regulator of calmodulin signaling.
Kleerekoper QK, Putkey JA.
J Biol Chem 284(12):7455-64. Epub 2008 Dec 23. 2009
41CALM1, DOC2A
Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry.
Dimova K, Kalkhof S, Pottratz I, Ihling C, Rodriguez-Castaneda F, Liepold T, Griesinger C, Brose N, Sinz A, Jahn O.
Biochemistry 48(25):5908-21. 2009
42CALM1, KRAS
The hypervariable region of K-Ras4B is responsible for its specific interactions with calmodulin.
Abraham SJ, Nolet RP, Calvert RJ, Anderson LM, Gaponenko V.
Biochemistry 48(32):7575-83. 2009
43CALM1, WFS1
Identification and characterization of wolframin, the product of the wolfram syndrome gene (WFS1), as a novel calmodulin-binding protein.
Yurimoto S, Hatano N, Tsuchiya M, Kato K, Fujimoto T, Masaki T, Kobayashi R, Tokumitsu H.
Biochemistry 48(18):3946-55. 2009
44CALM1, CALM2, CALM3
A new polymorphism in human calmodulin III gene promoter is a potential modifier gene for familial hypertrophic cardiomyopathy.
Friedrich FW, Bausero P, Sun Y, Treszl A, Krämer E, Juhr D, Richard P, Wegscheider K, Schwartz K, Brito D, Arbustini E, Waldenström A, Isnard R, Komajda M, Eschenhagen T, Carrier L; EUROGENE Heart Failure Project.
Eur Heart J 30(13):1648-55. doi: 10.1093/eurheartj/ehp153. Epub 2009 May 8. 2009
45CALM1, GRM5
Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5.
Lee JH, Lee J, Choi KY, Hepp R, Lee JY, Lim MK, Chatani-Hinze M, Roche PA, Kim DG, Ahn YS, Kim CH, Roche KW.
Proc Natl Acad Sci U S A 105(34):12575-80. Epub 2008 Aug 20. 2008
46CALM1, MBP
Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure.
Majava V, Petoukhov MV, Hayashi N, Pirilä P, Svergun DI, Kursula P.
BMC Struct Biol 8:10. 2008
47CALM1, CFLAR
Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling.
Pawar PS, Micoli KJ, Ding H, Cook WJ, Kappes JC, Chen Y, McDonald JM.
Biochem J 412(3):459-68.PMID: 18257744 2008
48CALM1
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.
Labasque M, Reiter E, Becamel C, Bockaert J, Marin P.
Mol Biol Cell. 19(11):4640-50. 2008
49CALM1, GJA1
Identification of the calmodulin binding domain of connexin 43.
Zhou Y, Yang W, Lurtz MM, Ye Y, Huang Y, Lee HW, Chen Y, Louis CF, Yang JJ.
J Biol Chem 282(48):35005-17. Epub 2007 Sep 27. 2007
50CALM1
A calmodulin-binding site on cyclin E mediates Ca2+-sensitive G1/s transitions in vascular smooth muscle cells.
Choi J, Chiang A, Taulier N, Gros R, Pirani A, Husain M.
Circ Res. 98(10):1273-81. 2006
51CALM1
A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
Mototani H, Mabuchi A, Saito S, Fujioka M, Iida A, Takatori Y, Kotani A, Kubo T, Nakamura K, Sekine A, Murakami Y, Tsunoda T, Notoya K, Nakamura Y, Ikegawa S.
Hum Mol Genet 14(8):1009-17. Epub 2005 Mar 3. 2005
52CALM1, EPOR, JAK2
Calmodulin physically interacts with the erythropoietin receptor and enhances Jak2-mediated signaling.
Kakihana K, Yamamoto M, Iiyama M, Miura O.
Biochem Biophys Res Commun 335(2):424-31. 2005
53CALM1
Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway.
Obata K, Nagata K, Iwase M, Odashima M, Nagasaka T, Izawa H, Murohara T, Yamada Y, Yokota M.
Biochem Biophys Res Commun 338(2):1299-305. Epub 2005 Oct 24. 2005
54CALM1, CERK
Calmodulin is involved in the Ca2+-dependent activation of ceramide kinase as a calcium sensor.
Mitsutake S, Igarashi Y.
J Biol Chem 280(49):40436-41. Epub 2005 Oct 3. 2005
55CALM1
The adaptor Grb7 is a novel calmodulin-binding protein: functional implications of the interaction of calmodulin with Grb7.
Li H, Sánchez-Torres J, del Carpio AF, Nogales-González A, Molina-Ortiz P, Moreno MJ, Török K, Villalobo A.
Oncogene. 24(26):4206-19. 2005
56CALM1
Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin.
Sidhu RS, Clough RR, Bhullar RP.
J Biol Chem. 280(23):21933-41. 2005
57CALM1
Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin.
Young KA, Caldwell JH.
J Physiol. 565(Pt 2):349-70. 2005
58CALM1, CDK5R1, CFHR1, FGF13, GABRB3, HBB, MAP1B, MAP2, MAP2K4, RAB6A, RAP2A, SCN2B, SORT1, SYN2, VAMP1, YWHAZ, ZBTB18
Gene regulation and DNA damage in the ageing human brain.
Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J, Yankner BA.
Nature 429(6994):883-91. Epub 2004 Jun 09. 2004
59CALM1
Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cells.
Cifuentes E, Mataraza JM, Yoshida BA, Menon M, Sacks DB, Barrack ER, Reddy GP.
Proc Natl Acad Sci U S A. 101(2):464-9. 2004
60CALM1
Calmodulin binding to the Fas death domain. Regulation by Fas activation.
Ahn EY, Lim ST, Cook WJ, McDonald JM.
J Biol Chem. 279(7):5661-6. 2004
61CALM1
Endogenous calmodulin interacts with the epidermal growth factor receptor in living cells.
Li H, Ruano MJ, Villalobo A.
FEBS Lett. 559(1-3):175-80. 2004
62CALM1
Calmodulin regulates transglutaminase 2 cross-linking of huntingtin.
Zainelli GM, Ross CA, Troncoso JC, Fitzgerald JK, Muma NA.
J Neurosci. 24(8):1954-61. 2004
63CALM1, RYR1, RYR2
Molecular basis of calmodulin binding to cardiac muscle Ca(2+) release channel (ryanodine receptor).
Yamaguchi N, Xu L, Pasek DA, Evans KE, Meissner G.
J Biol Chem 278(26):23480-6. Epub 2003 Apr 21. 2003
64REL, RELA, CALM1
Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.
Antonsson A, Hughes K, Edin S, Grundstršm T.
Mol Cell Biol 23(4):1418-27. 2003
65CALM1, ESRRG
Characterization of calmodulin binding to the orphan nuclear receptor Errgamma.
Hentschke M, Schulze C, SŸsens U, Borgmeyer U.
Biol Chem 384(3):473-82. 2003
66CALM1, PCP4
A new role for IQ motif proteins in regulating calmodulin function.
Putkey JA, Kleerekoper Q, Gaertner TR, Waxham MN.
J Biol Chem 278(50):49667-70. Epub 2003 Oct 9. 2003
67CALM1
Calcium/calmodulin modulation of olfactory and rod cyclic nucleotide-gated ion channels.
Trudeau MC, Zagotta WN.
J Biol Chem. 278(21):18705-8. 2003
68CALM1
A noncontiguous, intersubunit binding site for calmodulin on the skeletal muscle Ca2+ release channel.
Zhang H, Zhang JZ, Danila CI, Hamilton SL.
J Biol Chem. 278(10):8348-55. 2003
69CALM1
Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.
Strotmann R, Schultz G, Plant TD.
J Biol Chem. 278(29):26541-9. 2003
70CALM1
Structural determinant of TRPV1 desensitization interacts with calmodulin.
Numazaki M, Tominaga T, Takeuchi K, Murayama N, Toyooka H, Tominaga M.
Proc Natl Acad Sci U S A. 100(13):8002-6. 2003
71CALM1, PPEF1
Protein Ser/Thr phosphatases PPEF interact with calmodulin.
Kutuzov MA, Solov'eva OV, Andreeva AV, Bennett N.
Biochem Biophys Res Commun 293(3):1047-52. 2002
72CALM1
Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway.
Tebar F, Villalonga P, Sorkina T, Agell N, Sorkin A, Enrich C.
Mol Biol Cell 13(6):2057-68. 2002
73CALM1
Calmodulin is a selective modulator of estrogen receptors.
García Pedrero JM, Del Rio B, Martínez-Campa C, Muramatsu M, Lazo PS, Ramos S.
Mol Endocrinol. 16(5):947-60. 2002
74CALM1, KCNQ5
The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels.
Yus-Najera E, Santana-Castro I, Villarroel A.
J Biol Chem. 277(32):28545-53 2002
75CALM1
Presence of cyclic nucleotide phosphodiesterases PDE1A, existing as a stable complex with calmodulin, and PDE3A in human spermatozoa.
Lefičvre L, de Lamirande E, Gagnon C.
Biol Reprod. 67(2):423-30. 2002
76CALM1
Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets.
Clough RR, Sidhu RS, Bhullar RP.
J Biol Chem. 277(32):28972-80. 2002
77CALM1, CALM2, CALM3, RAB3B
Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin.
Sidhu RS, Bhullar RP.
Biochem Biophys Res Commun 289(5):1039-43. 2001
78CALM1, MAP2, MYO7A
Myosin VIIA is specifically associated with calmodulin and microtubule-associated protein-2B (MAP-2B).
Todorov PT, Hardisty RE, Brown SD.
Biochem J. 354(Pt 2):267-74. 2001
79CALM1
Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling.
Villalonga P, López-Alcalá C, Bosch M, Chiloeches A, Rocamora N, Gil J, Marais R, Marshall CJ, Bachs O, Agell N.
Mol Cell Biol. 21(21):7345-54. 2001
80CALM1
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Schumacher MA, Rivard AF, Bächinger HP, Adelman JP.
Nature. 410(6832):1120-4. 2001
81CALM1
Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.
Wang D, Quillan JM, Winans K, Lucas JL, Sadée W.
J Biol Chem. 276(37):34624-30. 2001
82CALM1
Kinase recognition by calmodulin: modeling the interaction with the autoinhibitory region of human cardiac titin kinase.
Amodeo P, Castiglione Morelli MA, Strazzullo G, Fucile P, Gautel M, Motta A.
J Mol Biol. 306(1):81-95. 2001
83CALM1
Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin.
Niemeyer BA, Bergs C, Wissenbach U, Flockerzi V, Trost C.
Proc Natl Acad Sci U S A. 98(6):3600-5. 2001
84CALM1, STRN, STRN3, STRN4
Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain.
Castets F, Rakitina T, Gaillard S, Moqrich A, Mattei MG, Monneron A.
J Biol Chem 275(26):19970-7. 2000
85CALM1, DCTN2, MARCKS, MARCKSL1
Protein kinase C-regulated dynamitin-macrophage-enriched myristoylated alanine-rice C kinase substrate interaction is involved in macrophage cell spreading.
Yue L, Lu S, Garces J, Jin T, Li J.
J Biol Chem 275(31):23948-56. 2000
86CALM1, CALM3, NEUROD1, TCF4
A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors.
Onions J, Hermann S, Grundstrom T.
Biochemistry 39(15):4366-74. 2000
87CALM1
Interaction between endothelial differentiation-related factor-1 and calmodulin in vitro and in vivo.
Mariotti M, De Benedictis L, Avon E, Maier JA.
J Biol Chem. 275(31):24047-51 2000
88CALM1
Calmodulin binds to and inhibits the activity of the membrane distal catalytic domain of receptor protein-tyrosine phosphatase alpha.
Liang L, Lim KL, Seow KT, Ng CH, Pallen CJ.
J Biol Chem. 275(39):30075-81. 2000
89CALM1, DLG4, PSD95
Interaction of NE-dlg/SAP102, a neuronal and endocrine tissue-specific membrane-associated guanylate kinase protein, with calmodulin and PSD-95/SAP90. A possible regulatory role in molecular clustering at synaptic sites.
Masuko N, Makino K, Kuwahara H, Fukunaga K, Sudo T, Araki N, Yamamoto H, Yamada Y, Miyamoto E, Saya H.
J Biol Chem. 274(9):5782-90 1999
90CALM1
Calmodulin-binding sites on adenylyl cyclase type VIII.
Gu C, Cooper DM.
J Biol Chem. 274(12):8012-21. 1999
91CALM1
Tyrosine phosphorylation modulates the interaction of calmodulin with its target proteins.
Corti C, Leclerc L'Hostis E, Quadroni M, Schmid H, Durussel I, Cox J, Dainese Hatt P, James P, Carafoli E.
Eur J Biochem. 262(3):790-802. 1999
92CALM1
Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCa1.
Fanger CM, Ghanshani S, Logsdon NJ, Rauer H, Kalman K, Zhou J, Beckingham K, Chandy KG, Cahalan MD, Aiyar J.
J Biol Chem. 274(9):5746-54. 1999
93CALM1
Interactions between neurogranin and calmodulin in vivo.
Prichard L, Deloulme JC, Storm DR.
J Biol Chem. 274(12):7689-94. 1999
94CALM1
In vivo and in vitro association of 14-3-3 epsilon isoform with calmodulin: implication for signal transduction and cell proliferation.
Luk SC, Ngai SM, Tsui SK, Fung KP, Lee CY, Waye MM.
J Cell Biochem. 73(1):31-5. 1999
95CALM1
Minimum CAG repeat in the human calmodulin-1 gene 5' untranslated region is required for full expression.
Toutenhoofd SL, et al.
Biochim Biophys Acta 1398 : 315-320. 1998
96CALM1, CALM2, CALM3
Characterization of the human CALM2 calmodulin gene and comparison of the transcriptional activity of CALM1, CALM2 and CALM3.
Toutenhoofd SL, Foletti D, Wicki R, Rhyner JA, Garcia F, Tolon R, Strehler EE.
Cell Calcium 23(5):323-38. 1998
97CALM1
Calmodulin is essential for cyclin-dependent kinase 4 (Cdk4) activity and nuclear accumulation of cyclin D1-Cdk4 during G1.
Taulés M, Rius E, Talaya D, López-Girona A, Bachs O, Agell N.
J Biol Chem. 273(50):33279-86. 1998
98CALM1, GRK1, GRK5, RCVRN
Localization of the sites for Ca2+-binding proteins on G protein-coupled receptor kinases.
Levay K, Satpaev DK, Pronin AN, Benovic JL, Slepak VZ.
Biochemistry. 37(39):13650-9. 1998
99CALM1
Alpha1-syntrophin has distinct binding sites for actin and calmodulin.
Iwata Y, Pan Y, Yoshida T, Hanada H, Shigekawa M.
FEBS Lett. 423(2):173-7. 1998
100AKAP5, CALM1
Regulation of the AKAP79-protein kinase C interaction by Ca2+/Calmodulin.
Faux MC, Scott JD.
J Biol Chem. 272(27):17038-44. 1997
101CALM1
Tryptophan residues in caldesmon are major determinants for calmodulin binding.
Graether SP, Heinonen TY, Raharjo WH, Jin JP, Mak AS.
Biochemistry. 36(2):364-9. 1997
102CALM1
The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain.
Deloulme JC, Prichard L, Delattre O, Storm DR.
J Biol Chem. 272(43):27369-77. 1997
103CALM1
G protein-coupled receptor kinase GRK4. Molecular analysis of the four isoforms and ultrastructural localization in spermatozoa and germinal cells.
Sallese M, Mariggiň S, Collodel G, Moretti E, Piomboni P, Baccetti B, De Blasi A.
J Biol Chem. 272(15):10188-95. 1997
104CALM1
Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membrane.
Wang KL, Khan MT, Roufogalis BD.
J Biol Chem. 272(25):16002-9. 1997
105CALM1
Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II.
Moyers JS, Bilan PJ, Zhu J, Kahn CR.
J Biol Chem. 272(18):11832-9. 1997
106CALM1, HD, HTT
Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin.
Bao J, et al.
Proc Natl Acad Sci U S A 93(10):5037-42. 1996
107CALM1, CDC42, IQGAP1, IQGAP2
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.
Brill S, Li S, Lyman CW, Church DM, Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ.
Mol Cell Biol 16(9):4869-78. 1996
108CALM1
Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit.
Ehlers MD, Zhang S, Bernhadt JP, Huganir RL.
Cell. 84(5):745-55. 1996
109CALM1, IQGAP1
IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs.
Hart MJ, Callow MG, Souza B, Polakis P.
EMBO J. 15(12):2997-3005. 1996
110CALM1
Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.
Lee CH, Della NG, Chew CE, Zack DJ.
J Neurosci. 16(21):6784-94. 1996
111CALM1
Use of a two-hybrid system to investigate molecular interactions of GAP-43.
Chao S, Benowitz LI, Krainc D, Irwin N.
Brain Res Mol Brain Res. 40(2):195-202. 1996
112CALM1
The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains.
Yokokura H, Picciotto MR, Nairn AC, Hidaka H.
J Biol Chem. 270(40):23851-9. 1995
113CALM1
The interaction of calmodulin with clathrin-coated vesicles, triskelions, and light chains. Localization of a binding site.
Pley UM, Hill BL, Alibert C, Brodsky FM, Parham P.
J Biol Chem. 270(5):2395-402. 1995
114CALM1
Evidence for a functional interaction between calmodulin and the glucocorticoid receptor.
Ning YM, Sánchez ER.
Biochem Biophys Res Commun. 208(1):48-54. 1995
115CALM1, CALM1P1, CALM1P2
Structure of the human CALM1 calmodulin gene and identification of two CALM1-related pseudogenes CALM1P1 and CALM1P2.
Rhyner JA, Ottiger M, Wicki R, Greenwood TM, Strehler EE.
Eur J Biochem 225(1):71-82. 1994
116CALM1
Regulation of p68 RNA helicase by calmodulin and protein kinase C.
Buelt MK, Glidden BJ, Storm DR.
J Biol Chem. 269(47):29367-70. 1994
117CALM1, CALM2, CALM3
Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3.
Berchtold MW, et al.
Genomics 16 : 461-465. 1993
118CALM1
Interaction of calmodulin with lactoferrin.
de Lillo A, Tejerina JM, Fierro JF.
FEBS Lett. 298(2-3):195-8. 1992
119CALM1, MIP
Calmodulin interacts with a C-terminus peptide from the lens membrane protein MIP26.
Girsch SJ, Peracchia C.
Curr Eye Res. 10(9):839-49. 1991
120CALM1, CALM2, CALM3
Multiple mRNAs encoding human calmodulin.
Pegues JC, Friedberg F.
Biochem Biophys Res Commun 172(3):1145-9. 1990
121CALM1, MAPT
Calmodulin binds to a tubulin binding site of the microtubule-associated protein tau.
Padilla R, Maccioni RB, Avila J.
Mol Cell Biochem. 97(1):35-41. 1990
122CALM1
Smooth muscle calponin. Inhibition of actomyosin MgATPase and regulation by phosphorylation.
Winder SJ, Walsh MP.
J Biol Chem. 265(17):10148-55. 1990
123CALM1
Studies of the interaction of troponin I with proteins of the I-filament and calmodulin.
Moir AJ, Ordidge M, Grand RJ, Trayer IP, Perry SV.
Biochem J. 209(2):417-26. 1983