Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PRKAG2 | contributors: mct/npt - updated : 30-11-2009 |
HGNC name | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
HGNC id | 9386 |
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Corresponding disease |
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Location | 7q36.1 Physical location : 151.253.202 - 151.574.316 | ||||
Synonym name | |||||
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Synonym symbol(s) | AMPKG2, CMH6, AAKG, AAKH, AAKG2, H91620p |
DNA |
TYPE | functioning gene |
STRUCTURE | 321.12 kb 16 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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text structure | (PRKAG2b) |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D7S2426 - D7S605 - D7S636 - D7S642 - D7S2641 - D7S2439 - PRKAG2 - RHEB - D7S2462 - D7S483 - D7S798 - qter |
Authors | Lang (00) Gollog (01) |
RNA |
TRANSCRIPTS | type | messenger |
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text | may be other transcripts (Lang) 63rd |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | pregnancy |
Text | placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | heteromer , trimer |
HOMOLOGY |
interspecies | ortholog to rattus Prkag2 (98.5pc) |
ortholog to murine Prkag2 (93.8pc) |
intraspecies | homolog to PRKAG1 |
Homologene |
FAMILY |
CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic | |
intracellular,nucleus,nucleoplasm |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | lipid/lipoprotein |
signaling |
fatty acid biosynthesis ; cholesterol biosynthesis |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
activated by | cAMP |
ASSOCIATED DISORDERS |
corresponding disease(s) | WPW , GSDH |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |