protein
| inhibiting SPI1 (PU1) and influencing cell fate and directing the development to the granulocyte lineage |
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binds KLF3 and both are implicated in controlling adipogenesis |
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functional interaction with CDX1 and PPARG |
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(CDX1 enhanced the expression of PPARG, a master transcriptional regulator of intestinal differentiation, at the transcriptional level, via functional interaction with CEBPA) |
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TCERG1 functions as an inhibitor of CEBPA rather than a transcriptional co-repressor, and inhibits CEBPA activity by keeping it retained in inactive, pericentromeric heterochromatin |
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substrate for FBXW7 (FBXW7 is a negative regulator of CEBPA function by targeting it to phosphorylation-dependent degradation) |
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interacting with HDAC9 (induction of adipogenic differentiation promotes HDAC9 down-regulation and replacement by EP300 at the E-box site of the CEBPA gene promoter, thus switching on adipogenic gene expression) |
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PTPN11 is required for induction of CEBPA expression and granulopoiesis in response to G-CSF or other cytokines independent of PTPN11-mediated ERK activation 8) |
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FABP1 is regulated by liver-enriched transcription factors FOXA2 and CEBPA |
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in committed macrophage progenitors, CEBPA-activated QKI negatively regulates macrophage differentiation by down-regulating CSF1R expression, forming a negative feedback loop during macrophage differentiation |
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ATF3 may contribute to the inhibition of adipocyte differentiation in hypoxia through downregulation of CEBPA expression |
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DICER1 might have important roles in the expression of adipogenic genes including PPARG and CEBPA via regulation of the expression of miRNAs at the early, but not the late, stage of adipocyte differentiation |
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TET2 helps CEBPA rapidly derepress myeloid genes during the conversion of pre-B cells into macrophages |
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DDIT3 is necessary for suppression of genes encoding the transcriptional master regulators of lipid metabolism: CEBPA, PPARA, and SREBF1 |
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UBE3A may negatively control adipogenesis by inhibiting CEBPA expression by targeting it to ubiquitin-proteasome pathway for degradation |
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RARA-ZBTB16 acts as a modifier oncogene that subverts differentiation in the granulocytic lineage by associating with CEBPA and inhibiting its activity |
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MBD2 colocalizes with the transcription factor CEBPA, and MBD2 binding at these positions is reduced upon CEBPA depletion |
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IKZF1 is a suppressor of basophil differentiation under steady-state conditions and that it acts by regulating permissive chromatin modifications of CEBPA |
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CEBPA interacts with the ETS domain of widely expressed GABPA, which leads to cooperative transcriptional activation of the myeloid-specific promoter for FCAR in part by facilitating recruitment of CEBPA to the promoter |
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CEBPA binding initiates chromatin relaxation and transcription, which are followed by DNA demethylation around a CEBPA binding site and a transcription start site in the AGT promoter |
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plays a dual role as an activator and as a repressor of GNAI2 gene transcription |
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regulatory role of CEBPA on VCAM1 expression |
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dual roles for JMJD6 in promoting adipogenic gene expression program by post-transcriptional regulation of CEBPB and CEBPD and direct transcriptional activation of PPARG2 and CEBPA during adipocyte differentiation |
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SOX6 regulates adipogenesis in vertebrate species by activating adipogenic regulators including PPARG, CEBPA and MEST |