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| homozygous Tcf3 mutant mice develop to full term without apparent abnormalities, but then display a high rate of postnatal death  | |
E2A-null mutant mice fail to generate mature B cells |
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homozygous Tcf3 mutant mice show retarded postnatal growth with blocking B cell differentiation |
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mice expressing the E2A-HLF fusion gene using Ig enhancer and promoter exhibit abnormal development in the thymus and spleen and are susceptible to infection |
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Tcf3/4-null primary mouse keratinocyte cultures show a growth defect with inability to maintain long-term epidermal homeostasis |