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FLASH GENE

Symbol

LIN7B

contributors: - updated : 26-08-2005

HGNC name	lin-7 homolog B (C. elegans)
HGNC id	17788

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a PDZ domain

mono polymer

heteromer , trimer

HOMOLOGY

interspecies

homolog to C.elegans LIN-7

Homologene

FAMILY

CATEGORY

regulatory , structural protein

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,membrane
text	localizing in synapses

basic FUNCTION

involved in regulation of synaptic function and synapse assembly

CELLULAR PROCESS

cell communication

PHYSIOLOGICAL PROCESS

nervous system , exocytosis transport , cellular trafficking transport

PATHWAY

metabolism

signaling

neurotransmission

a component

heterotrimerizing with CASK,MINT1

INTERACTION

DNA

RNA

small molecule

protein	binding to proteins with E-T/S-R/X-V/I/L peptide sequences, like ionic channels and glutamate receptors, NR2B
	partner of BAIAP2 anchoring the actin-based membrane cytoskeleton at cell-cell contacts
	binding to GNG13

cell & other

REGULATION

induced by

Ca2+ calcineurin pathway

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS