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FLASH GENE
Symbol LIN7B contributors: - updated : 26-08-2005
HGNC name lin-7 homolog B (C. elegans)
HGNC id 17788
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a PDZ domain
mono polymer heteromer , trimer
HOMOLOGY
interspecies homolog to C.elegans LIN-7
Homologene
FAMILY
CATEGORY regulatory , structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
text localizing in synapses
basic FUNCTION involved in regulation of synaptic function and synapse assembly
CELLULAR PROCESS cell communication
PHYSIOLOGICAL PROCESS nervous system , exocytosis transport , cellular trafficking transport
PATHWAY
metabolism
signaling neurotransmission
a component heterotrimerizing with CASK,MINT1
INTERACTION
DNA
RNA
small molecule
protein
  • binding to proteins with E-T/S-R/X-V/I/L peptide sequences, like ionic channels and glutamate receptors, NR2B
  • partner of BAIAP2 anchoring the actin-based membrane cytoskeleton at cell-cell contacts
  • binding to GNG13
  • cell & other
    REGULATION
    induced by Ca2+ calcineurin pathway
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS