Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol LIN7B contributors: - updated : 26-08-2005
HGNC name lin-7 homolog B (C. elegans)
HGNC id 17788
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral cortex  
 brainhindbraincerebellum  
 braindiencephalonhypothalamus  
 brainhindbrainmedulla oblongata  
 brainbasal nucleistriatum  
Olfactoryolfactory bulb    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a PDZ domain
mono polymer heteromer , trimer
HOMOLOGY
interspecies homolog to C.elegans LIN-7
Homologene
FAMILY
CATEGORY regulatory , structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
text localizing in synapses
basic FUNCTION involved in regulation of synaptic function and synapse assembly
CELLULAR PROCESS cell communication
PHYSIOLOGICAL PROCESS nervous system , exocytosis transport , cellular trafficking transport
PATHWAY
metabolism
signaling neurotransmission
a component heterotrimerizing with CASK,MINT1
INTERACTION
DNA
RNA
small molecule
protein
  • binding to proteins with E-T/S-R/X-V/I/L peptide sequences, like ionic channels and glutamate receptors, NR2B
  • partner of BAIAP2 anchoring the actin-based membrane cytoskeleton at cell-cell contacts
  • binding to GNG13
  • cell & other
    REGULATION
    induced by Ca2+ calcineurin pathway
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS