basic FUNCTION
| preventing its polymerization to F-actin |
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key factor for dynamic rearrangements of the actin cytoskeleton |
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not required for actomyosin ring formation in dividing chondrocytes but necessary to generate sufficient force for abscission during late cytokinesis |
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regulates vascular endothelial cells migration, invasion and capillary morphogenesis through its interaction with both actin and proline-rich ligands |
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involved in angiotensin II-induced vascular smooth muscle cell proliferation |
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required for glial cell adhesion and radial migration of cerebellar granule neurons |
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functional role for both profilins (PFN1, PFN2) in neuronal nuclei |
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key player to control actin fiber structure, and it is involved in a number of cellular activities such as migration |
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critical molecule for the skeletal development, and this could be at least in part associated with the retardation of cell migration |
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crucial for the conversion of monomeric (G)-actin to filamentous (F)-actin |
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actin monomer-binding protein, linked to many cellular activities ranging from control of actin polymerization to gene transcription |
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actin-regulatory protein that has a role in modulating smooth muscle contraction |