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GENATLAS PHENOTYPE

last update : 14-12-2013

Symbol	ALS18
Location	17p13.2
Name	amyotrophic lateral sclerosis 18
Corresponding gene	PFN1
Main clinical features	neurodegenerative disorder characterized by the death of motor neurons in the brain, brainstem, and spinal cord, resulting in fatal paralysis limb onset, and age of onset for familial ALS18 cases was 44.8 +/- 7.4 years
Genetic determination	autosomal dominant
Function/system disorder	neurology
Type	disease

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