| 1 | CTTN, PFN1
|
| The association of cortactin with profilin-1 is critical for smooth muscle contraction.
|
| Wang R, Cleary RA, Wang T, Li J, Tang DD.
|
| J Biol Chem 289(20):14157-69. doi: 10.1074/jbc.M114.548099. Epub 2014 Apr 3.
2014
|
| 2 | PFN1
|
| Mutation analysis and immunopathological studies of PFN1 in familial and sporadic amyotrophic lateral sclerosis.
|
| Yang S, Fifita JA, Williams KL, Warraich ST, Pamphlett R, Nicholson GA, Blair IP.
|
| Neurobiol Aging 34(9):2235.e7-2235.e10. doi: 10.1016/j.neurobiolaging.2013.04.003. Epub 2013 Apr 28.
2013
|
| 3 | PFN1
|
| Profilin 1 potentiates apoptosis induced by staurosporine in cancer cells.
|
| Yao W, Cai X, Liu C, Qin Y, Cheng H, Ji S, Xu W, Wu C, Chen T, Xu J, Long J, Fang Z, Qu B, Hoth M, Ni Q, Zha X, Yu X.
|
| Curr Mol Med 13(3):417-28.
2013
|
| 4 | PFN1
|
| Screening of the PFN1 gene in sporadic amyotrophic lateral sclerosis and in frontotemporal dementia.
|
| Tiloca C, Ticozzi N, Pensato V, Corrado L, Del Bo R, Bertolin C, Fenoglio C, Gagliardi S, Calini D, Lauria G, Castellotti B, Bagarotti A, Corti S, Galimberti D, Cagnin A, Gabelli C, Ranieri M, Ceroni M, Siciliano G, Mazzini L, Cereda C, Scarpini E, Sorarù G, Comi GP, D'Alfonso S, Gellera C, Ratti A, Landers JE, Silani V; SLAGEN Consortium.
|
| Neurobiol Aging 34(5):1517.e9-10. doi: 10.1016/j.neurobiolaging.2012.09.016. Epub 2012 Oct 11.
2013
|
| 5 | PFN1
|
| Mutation analysis of PFN1 in familial amyotrophic lateral sclerosis patients.
|
| Daoud H, Dobrzeniecka S, Camu W, Meininger V, Dupré N, Dion PA, Rouleau GA.
|
| Neurobiol Aging 34(4):1311.e1-2. doi: 10.1016/j.neurobiolaging.2012.09.001. Epub 2012 Oct 10.
2013
|
| 6 | PFN1, PFN2
|
| Neuronal profilin isoforms are addressed by different signalling pathways.
|
| Murk K, Wittenmayer N, Michaelsen-Preusse K, Dresbach T, Schoenenberger CA, Korte M, Jockusch BM, Rothkegel M.
|
| PLoS One 7(3):e34167. doi: 10.1371/journal.pone.0034167. Epub 2012 Mar 28.
2012
|
| 7 | PFN1
|
| Molecular insights on context-specific role of profilin-1 in cell migration.
|
| Ding Z, Bae YH, Roy P.
|
| Cell Adh Migr 6(5):442-9. doi: 10.4161/cam.21832. Epub 2012 Sep 1. Review.
2012
|
| 8 | PFN1
|
| Stimulus-dependent phosphorylation of profilin-1 in angiogenesis.
|
| Fan Y, Arif A, Gong Y, Jia J, Eswarappa SM, Willard B, Horowitz A, Graham LM, Penn MS, Fox PL.
|
| Nat Cell Biol 14(10):1046-56. doi: 10.1038/ncb2580. Epub 2012 Sep 23.
2012
|
| 9 | PFN1
|
| Profilin1 regulates sternum development and endochondral bone formation.
|
| Miyajima D, Hayata T, Suzuki T, Hemmi H, Nakamoto T, Notomi T, Amagasa T, Böttcher RT, Costell M, Fässler R, Ezura Y, Noda M.
|
| J Biol Chem 287(40):33545-53. Epub 2012 Jul 6.
2012
|
| 10 | ALS18, PFN1
|
| Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis.
|
| Wu CH, Fallini C, Ticozzi N, Keagle PJ, Sapp PC, Piotrowska K, Lowe P, Koppers M, McKenna-Yasek D, Baron DM, Kost JE, Gonzalez-Perez P, Fox AD, Adams J, Taroni F, Tiloca C, Leclerc AL, Chafe SC, Mangroo D, Moore MJ, Zitzewitz JA, Xu ZS, van den Berg LH, Glass JD, Siciliano G, Cirulli ET, Goldstein DB, Salachas F, Meininger V, Rossoll W, Ratti A, Gellera C, Bosco DA, Bassell GJ, Silani V, Drory VE, Brown RH Jr, Landers JE.
|
| Nature 488(7412):499-503. doi: 10.1038/nature11280.
2012
|
| 11 | NACC1, PFN1
|
| NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells.
|
| Yap KL, Fraley SI, Thiaville MM, Jinawath N, Nakayama K, Wang J, Wang TL, Wirtz D, Shih IeM.
|
| Cancer Res 72(16):4085-96. doi: 10.1158/0008-5472.CAN-12-0302.
2012
|
| 12 | PFN1
|
| Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons.
|
| Kullmann JA, Neumeyer A, Gurniak CB, Friauf E, Witke W, Rust MB.
|
| EMBO Rep 13(1):75-82. doi: 10.1038/embor.2011.211.
2011
|
| 13 | PFN1
|
| Involvement of profilin-1 in angiotensin II-induced vascular smooth muscle cell proliferation.
|
| Cheng JF, Ni GH, Chen MF, Li YJ, Wang YJ, Wang CL, Yuan Q, Shi RZ, Hu CP, Yang TL.
|
| Vascul Pharmacol 55(1-3):34-41. doi: 10.1016/j.vph.2011.04.003. Epub 2011 May 6.
2011
|
| 14 | PFN1
|
| Profilin 1 overexpression in renal cell carcinoma.
|
| Minamida S, Iwamura M, Kodera Y, Kawashima Y, Ikeda M, Okusa H, Fujita T, Maeda T, Baba S.
|
| Int J Urol 18(1):63-71. doi: 10.1111/j.1442-2042.2010.02670.x. Epub 2010 Nov 22.
2011
|
| 15 | PFN1
|
| Microtubule-dependent localization of profilin I mRNA to actin polymerization sites in serum-stimulated cells.
|
| Johnsson AK, Karlsson R.
|
| Eur J Cell Biol 89(5):394-401. doi: 10.1016/j.ejcb.2009.10.020. Epub 2010 Feb 2.
2010
|
| 16 | PFN1
|
| How ILK and kindlins cooperate to orchestrate integrin signaling.
|
| Böttcher RT, Lange A, Fässler R.
|
| Curr Opin Cell Biol urr Opin Cell Biol. 2009 Jun 25. [Epub ahead of print]
2009
|
| 17 | PFN1
|
| Both actin and polyproline interactions of profilin-1 are required for migration, invasion and capillary morphogenesis of vascular endothelial cells.
|
| Ding Z, Gau D, Deasy B, Wells A, Roy P.
|
| Exp Cell Res 315(17):2963-73. doi: 10.1016/j.yexcr.2009.07.004. Epub 2009 Jul 14.
2009
|
| 18 | HTT, PFN1, PFN2, ROCK1
|
| Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation.
|
| Shao J, Welch WJ, Diprospero NA, Diamond MI.
|
| Mol Cell Biol 28(17):5196-208. doi: 10.1128/MCB.00079-08. Epub 2008 Jun 23. 2008
|
| 19 | PFN1
|
| Profilin-1 is a negative regulator of mammary carcinoma aggressiveness.
|
| Zou L, Jaramillo M, Whaley D, Wells A, Panchapakesa V, Das T, Roy P.
|
| Br J Cancer 97(10):1361-71. Epub 2007 Oct 16.
2007
|
| 20 | PFN1
|
| Profilin is an effector for Daam1 in non-canonical Wnt signaling and is required for vertebrate gastrulation.
|
| Sato A, Khadka DK, Liu W, Bharti R, Runnels LW, Dawid IB, Habas R.
|
| Development 133(21):4219-31. Epub 2006 Oct 4.
2006
|
| 21 | PFN1
|
| Profilin-I-ligand interactions influence various aspects of neuronal differentiation.
|
| Lambrechts A, Jonckheere V, Peleman C, Polet D, De Vos W, Vandekerckhove J, Ampe C.
|
| J Cell Sci 119(Pt 8):1570-8. Epub 2006 Mar 28.
2006
|
| 22 | PFN1
|
| The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner.
|
| Neuhoff H, Sassoè-Pognetto M, Panzanelli P, Maas C, Witke W, Kneussel M.
|
| Eur J Neurosci 21(1):15-25.
2005
|
| 23 | PFN1, DNM1, DNM2, CTTN
|
| Dynamin2 and cortactin regulate actin assembly and filament organization.
|
| Schafer DA, Weed SA, Binns D, Karginov AV, Parsons JT, Cooper JA.
|
| Curr Biol 12(21):1852-7. 2002
|
| 24 | MDS, PFN1
|
| Identification of the functional profilin gene, its localization to chromosome subband 17p13.3 and demonstration of its deletion in some patients with Miller-Dieker syndrome.
|
| Kwiatkowski DJ, et al.
|
| Am J Hum Genet 46 : 559-567. 1990
|
| 25 | PFN1, PFN2, PFNP1
|
| Human profilin. Molecular cloning, sequence comparison and chromosomal analysis.
|
| Kwiatkowski DJ, et al.
|
| J Biol Chem 263 : 5910-5915. 1988
|