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FLASH GENE

Symbol

CLDN2

contributors: mct/npt/pgu - updated : 21-07-2015

HGNC name	claudin 2
HGNC id	2041

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in breast carcinoma tumoral     --over   may be involved at early stages of transformation in inflammatory bowel disease -associated neoplasia tumoral     --over   may be closely correlated to gastric carcinogenesis constitutional     --low   in renal epithelial cells by metabolic acidosis tumoral     --over   in solar keratosis and skin squamous cell carcinomas compared to normal skin

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS