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FLASH GENE
Symbol CLDN2 contributors: mct/npt/pgu - updated : 21-07-2015
HGNC name claudin 2
HGNC id 2041
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in breast carcinoma
tumoral     --over  
may be involved at early stages of transformation in inflammatory bowel disease -associated neoplasia
tumoral     --over  
may be closely correlated to gastric carcinogenesis
constitutional     --low  
in renal epithelial cells by metabolic acidosis
tumoral     --over  
in solar keratosis and skin squamous cell carcinomas compared to normal skin
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS