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GENATLAS PHENOTYPE
last update : 28/11/2005
Symbol THPO
Location 3q27-q28
Name thrombocythemia, essential
Corresponding gene THPO
Main clinical features
  • myeloproliferative syndrome due to a sustained proliferation of megakaryocytes,resulting in thrombotic or hemorrhagic episodes and a risk of leukemia
  • Genetic determination autosomal dominant
    Function/system disorder hematology
    Type disease
    Gene product
    Name thrombopoietin, THPO, unlikely to be frequently involved