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GENATLAS PHENOTYPE

last update : 18-08-2011

Symbol	LAD1
Location	21q22.3
Name	leukocyte adhesion deficiency, type I
Other name(s)	lymphocyte function-associated antigen 1 immunodeficiency
Corresponding gene	ITGB2
Other symbol(s)	LAD-1, ITGB2, LAD
Main clinical features	bacterial, recurrent, severe life-threatening infections, chronic neutrophilia, and impaired wound healing associated with gingivoperiodontitis and lack of pus formation
Genetic determination	autosomal recessive
Function/system disorder	defense and immunity
Type	disease

Gene product

Name

ITGB2

Remark(s)