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GENATLAS PHENOTYPE
last update : 13/06/2006
Symbol ALPS2
Location 2q33-q34
Name autoimmune inherited lymphoproliferative syndrome, type II
Other name(s) autoimmune inherited lymphoproliferative syndrome, type IIA
Corresponding gene CASP10
Other symbol(s) ALPS2A
Main clinical features
  • abnormal lymphocyte and dendritic cell homeostasis and immune regulatory defects
    • Genetic determination autosomal dominant
    Function/system disorder defense and immunity
    Type disease
    Gene product
    Name caspase 10 (CASP10), missense mutations