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FLASH GENE
Symbol VGLL2 contributors: - updated : 15-10-2005
HGNC name vestigial like 2 (Drosophila)
HGNC id 20232
Location 6q22.31      Physical location : 117.586.720 - 117.594.727
Synonym name
  • transcription cofactor vestigial-like 2
  • SID (scalloped interaction domain)-containing protein
  • Synonym symbol(s) VGL2, VITO1
    DNA
    TYPE functioning gene
    STRUCTURE 8.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    NT5C2L1 6q22.31 5'-nucleotidase, cytosolic II-like 1 COL10A1 6q21-q22.3 collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia) TSPYL4 6q22.31 TSPY-like 4 RPS5P1 6q22.1-q22.3 ribosomal protein S5 pseudogene 1 TSPYL 6q21-q23 TSPY-like SART2 6q22 squamous cell carcinoma antigen recognized by T cells 2 LOC391964 6 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) C6orf187 6q22.31 chromosome 6 open reading frame 187 C6orf188 6q22.31 chromosome 6 open reading frame 188 C6orf78 6q22.31 chromosome 6 open reading frame 78 RWDD1 6q13-q22.33 RWD domain containing 1 RSHL3 6q22.31 radial spokehead-like 3 C6orf113 6q22.31 chromosome 6 open reading frame 113 KPNA5 6q22.31 karyopherin alpha 5 (importin alpha 6) C6orf189 6q22.31 chromosome 6 open reading frame 189 GPRC6A 6q22.31 G protein-coupled receptor, family C, group 6, member A RFXDC1 6q22.31 regulatory factor X domain containing 1 VGLL2 6q22.31 vestigial like 2 (Drosophila) ROS1 6q21-q22 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) DCBLD1 6q22.31 discoidin, CUB and LCCL domain containing 1 GOPC 6q21 golgi associated PDZ and coiled-coil motif containing LOC221308 6q22.31 similar to RIKEN cDNA 5730521E12 C6orf68 6q22.31 chromosome 6 open reading frame 68 SLC35F1 6q22.31 solute carrier family 35, member F1 LOC391965 6 hypothetical gene supported by BX647084
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1709 - 143 - Gunther
    - - 2212 33.4 317 - Gunther
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Nervousbrain    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal, pregnancy
    Text placenta, the differentiating somites and branchial arches during embryogenesis
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    SID (scalloped interaction) domain
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY motor/contractile
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text during muscle differentiation, VGLL2 mRNA levels increase and VGLL2 protein translocates from the cytoplasm to the nucleus
    basic FUNCTION playing an important role in the muscle differentiation and the development of skeletal muscles and of pharyngeal clefts/Rathke's pouch derived structures
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein a cofactor of TEF-1 and MEF2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS