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FLASH GENE
Symbol TSSK2 contributors: - updated : 06-10-2006
HGNC name testis specific serine threonine kinase 2
HGNC id 11401
Location 22q11.2      Physical location : 19.118.320 - 19.120.136
Synonym name
  • serine/threonine kinase 22B (spermiogenesis associated)
  • testis specific serine threonine kinase 2
  • Synonym symbol(s) TSKL, DGSG, SPOGA2, STK22B
    EC.number 2.7.1.37
    DNA
    TYPE functioning gene
    STRUCTURE 1.00 kb     1 Exon(s)
    MAPPING cloned Y linked   status provisional
    Map see DGCR
    regionally located transcript DGS-G, 1.8kb, from the DGCR minimal critical region
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • conserved kinase domains typical of the superfamily of Ser/Thr kinases
  • HOMOLOGY
    interspecies homolog to murine Stk22b
    Homologene
    FAMILY testis-specific serine/threonine (Ser/Thr) kinase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • serine/threonine kinase, involved in spermatogenesis (see D22S1572)
  • might play a role in sperm function (as other members of this family)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with TSKS
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS