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FLASH GENE
Symbol TKTL1 contributors: np - updated : 17-10-2005
HGNC name transketolase-like 1
HGNC id 11835
Location Xq28      Physical location : 153.524.026 - 153.558.712
Synonym name
  • transketolase 2
  • transketolase-related protein
    • Synonym symbol(s) TKR, TK3, TKT2, TK 2
    EC.number 2.2.1.1
    DNA
    TYPE functioning gene
    STRUCTURE 34.55 kb     13 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Map cen - RGCP@ - TKTL1 - FLNA - EMD EMD - DNASE1L1 - TAZ - qter
    Authors Coy (96)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2634 64.6 590 - -
    13 - 2652 65.2 596 - -
    - - 2579 59.2 540 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductivespermatogonia
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies homolog to transketolase
    Homologene
    FAMILY
  • transketolase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • thiamine-dependent enzyme that links the pentose phosphate pathway with the glycolytic pathway
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS