basic FUNCTION
| playing a regulatory role during development |
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plays an essential role in transcription activation mediated by nuclear receptors |
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probably acting as integral component of corepressor complexes that mediates the recruitment of the 19s proteasome complex, leading to the subsequent proteosomal degradation of transcription repressor complexes |
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key regulator of gene expression, and important gene in the appropriate control of gene expression (Parker 2008) |
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E3 ligase acting as a protein involved in BCL3 degradation through a GSK3-independent pathway |
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with CTBP1, are key regulators of different properties of the BCL3 oncoprotein |
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TBL1X and its highly related family member TBL1XR1 were required for Wnt-beta-catenin-mediated transcription |
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controls lipid mobilization in white adipose tissue |
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is essential for transcriptional repression mediated by unliganded nuclear receptors (NRs) and othe regulated transcription factors (TFs) |