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FLASH GENE
Symbol STAG3 contributors: - updated : 03-09-2007
HGNC name stromal antigen 3
HGNC id 11356
Location 7q22      Physical location : 99.775.537 - 99.812.010
Synonym name
  • stromalin 3
  • cohesin subunit SA-3
  • SCC3 homolog
  • DNA
    TYPE functioning gene
    STRUCTURE 36.00 kb     34 Exon(s)    3 Copie(s)
    10 Kb 5' upstream gene genomic sequence study
    text structure two related sequences STAG3L at 7q22, four in the WBS critical region (see STAG3l)
    MAPPING cloned Y linked N status provisional
    Physical map
    CYP3A7 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 7 CYP3A5P2 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 CYP3A4 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A43 7q21.1 cytochrome P450, family 3, subfamily A, polypeptide 43 TRIM4 7q22-q31.1 tripartite motif-containing 4 AZGP1 7q22.1 alpha-2-glycoprotein 1, zinc LOC392078 7 hypothetical gene supported by BC022382 ZNF36 7q21.3-q22.1 zinc finger protein 36 (KOX 18) ZNF38 7q21-q22 zinc finger protein 38 ZNF3 7q22.1 zinc finger protein 3 (A8-51) COPS6 7q22.1 zinc finger protein 3 (A8-51) MCM7 7q21.3-q22.1 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) AP4M1 7q22.1 adaptor-related protein complex 4, mu 1 subunit TAF6 7q11 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa MGC40499 7q22.1 hypothetical protein MGC40499 LOC255374 7q22.1 similar to hypothetical protein MGC49416 LOC392079 7 similar to ribosomal protein L7 LOC389541 7 similar to CG14977-PA FLJ10925 7q22.1 hypothetical protein FLJ10925 GAL3ST-4 7q22 hypothetical protein FLJ10925 GPC2 7q22.1 glypican 2 (cerebroglycan) STAG3 7q22 stromal antigen 3 GATS 7q22.1 opposite strand transcription unit to STAG3 LOC392080 7 similar to opposite strand transcription unit to Stag3; Gats protein PILRB 7q22.1 paired immunoglobin-like type 2 receptor beta PILRA 7q22 paired immunoglobin-like type 2 receptor alpha ZCWPW1 7q22.1 zinc finger, CW-type with PWWP domain 1 FLJ20257 7q22.1 hypothetical protein FLJ20257 MGC22793 7q22.1 hypothetical protein MGC22793 THG-1 7p21-p15 TSC-22-like FLJ37538 7q22.1 hypothetical protein FLJ37538
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node   highly
     tonsils   highly
    Nervousnervecranial nerve  highly
    Reproductivemale systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    life cycle division
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    specific stromalin conservative domain (SCD)
    HOMOLOGY
    Homologene
    FAMILY
  • stromalin family
  • SCC3 family
  • CATEGORY adhesion , antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    text synaptonemal complex
    basic FUNCTION
  • chromosome pairing and maintenance of synaptonemal complex structure during the pachytene phase of meiosis
  • meiosis-specific cohesin subunits, forming complexes involved in the maintenance of sister chromatid cohesion during division of somatic and germ cells with a sexual dimorphism in sister chromatid cohesion in meiosis
  • CELLULAR PROCESS cell cycle,division,meiosis
    nucleotide, chromatin organization
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component cohesin complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS