basic FUNCTION
| may be involved in pre-mRNA splicing |
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repressing hepatitis B virus (hbv) core promoter activity and transcription of hbv genes |
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and production of hbv virions |
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spliceosome-associated factor required for mitotic progression  |
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has a novel role in maintaining proper nuclear organization of pre-mRNA processing factors in nuclear speckles  |
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essential for appropriate subnuclear organization of pre-mRNA splicing factors and for promoting normal cell cycle progression  |
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large Ser/Arg (SR)-related protein, is a splicing cofactor contributing to efficient splicing of cell-cycle regulators  |
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facilitates the interaction of Ser/Arg proteins with RNA polymerase II and other key spliceosome components, suggesting its function in efficient cotranscriptional RNA processing  |
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plays a critical role in the proliferation, survival, and tumorigenicity of pancreatic cancer cells  |
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SON-mediated splicing is required for proper processing of selective transcripts related to cell cycle, microtubules, centrosome maintenance, and genome stability  |
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is an emerging player in gene regulation during cancer development and progression  |
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RNA splicing factor, controls MLL complex-mediated transcriptional initiation  |
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influence cell-cycle progression, genomic integrity, and maintenance of pluripotency in stem cell populations  |
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is a master regulator governing neurodevelopment and demonstrate the importance of SON-mediated RNA splicing in human development  |