protein
| binding and regulating activated insulin-like growth factor receptor 1 (IGF1R) |
|
mediating estrogen inhibition of GH1 signaling |
|
binding the erythropoietin receptor |
|
bind 2 phosphorylated tyrosines on the GH receptor |
|
interaction with ELOB/ELOC controls SOCS2 protein turnover and affects its molecular activity  |
|
SOCS2 negatively regulates FLT3 signaling by blocking activation of Erk 1/2 and STAT5  |
|
SOCS2-interacting protein, and binding requires the SOCS2 SH2 domain and EPHA2 activation loop autophosphorylation, which is stimulated by EFNA1 or by phosphotyrosine phosphatase inhibition  |