Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SETD2 | contributors: mct - updated : 11-05-2019 |
HGNC name | SET domain containing 2 |
HGNC id | 18420 |
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Corresponding disease |
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Location | 3p21.31 Physical location : 47.057.899 - 47.205.467 | ||
Synonym name | |||
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Synonym symbol(s) | HSPC069, KIAA1732, p231HBP, HYPB, FLJ45883, FLJ16420, FLJ22472, FLJ23184, HIF-1, KMT3A, SET2, HBP231, FLJ46217 | ||
EC.number | 2.1.1.43 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | head to head |
STRUCTURE | 147.57 kb 21 Exon(s) |
regulatory sequence | Binding site |
text structure | DNA binding site in the proximal E1A promoter |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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conjugated | PhosphoP |
HOMOLOGY |
interspecies | homolog to murine Setd2 (87.4pc) |
homolog to rattus Setd2 (80.8pc) |
Homologene |
FAMILY | |
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CATEGORY | enzyme , regulatory , tumor suppressor |
CELLULAR PROCESS | nucleotide, transcription, regulation |
nucleotide, RNA splicing |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | |
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INTERACTION |
DNA | |
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RNA |
small molecule |
cell & other |
REGULATION |
activated by | low charge region |
Other | may be automethylated |
ASSOCIATED DISORDERS |
corresponding disease(s) | STOL2 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene | ||
Marker
Therapy target
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ANIMAL & CELL MODELS |