Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SERPINI1 | contributors: mct/npt/shn - updated : 09-02-2013 |
HGNC name | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
HGNC id | 8943 |
|
Corresponding disease |
| ||
Location | 3q26.1 Physical location : 167.453.431 - 167.543.356 | ||
Synonym name | |||
| |||
| |||
| |||
| |||
Synonym symbol(s) | PI12, PI-12, DKFZp781N13156 |
DNA |
TYPE | functioning gene |
STRUCTURE | 89.93 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
Map | cen - D3S1264 - D3S1253 - SERPINI1 - D3S3622 - D3S1614 - qter |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
conjugated | GlycoP |
HOMOLOGY |
interspecies | ortholog to Serpini1, Mus musculus |
ortholog to Serpini1, Rattus norvegicus | |
ortholog to serpini1, Danio rerio | |
ortholog to SERPINI1, Pan troglodytes |
Homologene |
FAMILY |
CATEGORY | enzyme , regulatory |
SUBCELLULAR LOCALIZATION | extracellular |
text | localised to dense cored secretory vesicles in PC12 cells |
CELLULAR PROCESS | cell organization/biogenesis |
PHYSIOLOGICAL PROCESS | nervous system |
text | putative regulator of extracellular proteolysis at growth cones or synapses |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | FENIB |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |