protein
| interaction with MTOR on the outer membrane of the mitochondria is inhibited by KNK437 and triggers caspase-3 activation |
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IRS1 is a critical mediator of the myogenic functions of raptor and RHEB |
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SQSTM1 interacts in an amino acid-dependent manner with MTOR and RPTOR |
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RPTOR in MTOR complex 1 is believed to recruit EIF4EBP1, facilitating phosphorylation of EIF4EBP1 by the kinase MTOR |
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positive regulation of MTOR activity by NPRL2 is mediated through NPRL2 interaction with RPTOR |
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NPRL2 interacts with RPTOR in amino acid sufficiency to activate MTOR |