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FLASH GENE

Symbol

RPS20

contributors: mct - updated : 02-04-2017

HGNC name	ribosomal protein S20
HGNC id	10405

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	8q12.1      Physical location : 56.980.738 - 56.987.140
Synonym symbol(s)	GS00315, S20

DNA

TYPE	functioning gene
STRUCTURE	6.40 kb     6 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001023 4 - 857 NP_001014 - 119 - 1998 9582194 NM_001146227 6 - 1013 NP_001139699 - 142 - 1998 9582194

EXPRESSION

Type	ubiquitous

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

fetal

Text

pancreas

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

S10P family of ribosomal proteins

CATEGORY

structural protein , RNA associated

SUBCELLULAR LOCALIZATION	extracellular
	intracellular
	intracellular,cytoplasm,cytosolic,ribosome

basic FUNCTION

40S ribosomal protein S20

CELLULAR PROCESS

protein, translation/synthesis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

component of the small 40S ribosomal subunit

INTERACTION

DNA

RNA

binding

small molecule

protein

RPL37, RPS15 and RPS20 regulate the MDM2-TP53-MDM4 network

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in medulloblastoma is adversely associated with with adverse outcome

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	could serve as potential biomarkers of clear cell renal cell carcinoma (ccRCC)
Therapy target

ANIMAL & CELL MODELS