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Symbol RPS20 contributors: mct - updated : 02-04-2017
HGNC name ribosomal protein S20
HGNC id 10405
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY S10P family of ribosomal proteins
CATEGORY structural protein , RNA associated
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,cytosolic,ribosome
basic FUNCTION 40S ribosomal protein S20
CELLULAR PROCESS protein, translation/synthesis
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component component of the small 40S ribosomal subunit
INTERACTION
DNA
RNA binding
small molecule
protein
  • RPL37, RPS15 and RPS20 regulate the MDM2-TP53-MDM4 network
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in medulloblastoma is adversely associated with with adverse outcome
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
  • could serve as potential biomarkers of clear cell renal cell carcinoma (ccRCC)
  • Therapy target
    ANIMAL & CELL MODELS