basic FUNCTION
| may be playing an important role in eliminating peroxides generated during metabolism |
|
involved in redox regulation of the cell |
|
reducing peroxides with reducing equivalents provided through the thioredoxin system |
|
might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) |
|
enhancing natural killer (NK) cells activity |
|
acting as a negative regulator of PDGF signaling |
|
have a role in both the resistance of certain cancers to therapy and quite a different role in possibly slowing the progression of neurodegenerative diseases |
|
functioning as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte and having nonredundant role in erythrocyte defense against oxidative stress |
|
thiol-specific peroxidase, that regulate proinflammatory responses, vascular remodeling, and global oxidative stress |
|
pecific peroxidase that inhibits atherogenic responses in vascular and inflammatory cells |
|
has been shown to regulate diverse biological functions as cell proliferation and planar cell polarity, and also to affect wound healing |
|
PRDX2 functions are modulated in response to oxidative stress in diseased Red blood cells |
|
protects cells from deleterious oxidative damage |
|
PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia |
|
|