Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PGR | contributors: mct - updated : 22-06-2016 |
HGNC name | progesterone receptor |
HGNC id | 8910 |
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Location | 11q22.1 Physical location : 100.900.354 - 101.000.544 |
Synonym symbol(s) | PROGR, PR, NR3C3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 100.19 kb 8 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | Y | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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text | resulting from two distinct transcripts,transcribed from distinct promoters of PRG gene |
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to murine Pgr |
Homologene |
FAMILY | steroid/thyroid hormone receptor superfamily |
CATEGORY | transcription factor , signaling hormone , receptor |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm | |
intracellular,nucleus,nucleoplasm |
basic FUNCTION | |
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CELLULAR PROCESS
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nucleotide, transcription |
PHYSIOLOGICAL PROCESS | development , reproduction/sex |
text | puberty |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | ![]() |
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cell & other |
REGULATION |
Other | regulated by UBE3A (UBE3A controls mammary gland development by regulating PR-B protein turnover via the ubiquitin proteasome pathway) ![]() | |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to idiopathic recurrent pregnancy loss |
Variant & Polymorphism other | ![]() |
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Candidate gene | ![]() | |
Marker
Therapy target
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ANIMAL & CELL MODELS |