Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PDE4B | contributors: mct/npt/pgu - updated : 06-02-2018 |
HGNC name | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) |
HGNC id | 8781 |
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Location | 1p31.3 Physical location : 66.258.192 - 66.840.261 |
Synonym name | |
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Synonym symbol(s) | DPDE4, MGC126529, PDEIVB, DKFZp686F2182, PDE32, PDE4B5 |
EC.number | 3.1.4.17/ 3.1.4.53 |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | head to head |
STRUCTURE | 582.07 kb 17 Exon(s) |
Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
motif | Viral sequence long terminal repeat |
text structure | specific HERV-K LTR 50 kb downstream |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | pter - D1S2886 - D1S2866 - PDE4B - D1S198 - D1S3166 - cen |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to Drosophila dunce gene |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic,vesicle | |
intracellular,cytoplasm,cytoskeleton,microtubule,centrosome | |
intracellular,nucleus | |
text | abundant in synaptosomes |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
inhibited by | rolipram |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to schizophrenia (through binding with DISC1) |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |