basic FUNCTION
| cadherin-related neuronal receptor, putatively involved in the specificity of neuronal connections |
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essential for both elongation of striatal axons and patterning of the putative guidance cues for thalamocortical projections |
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cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain |
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PCDH10 is involved in angiogenesis and methylation correlated with multiple myeloma |
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PCDH10 is primarily required for linking ubiquitinated DLG4 to the proteasomal machinery |
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distinct roles for MEF2A, PCDH10 and FMR1 in regulated degradation of DLG4 and synapse elimination, suggesting a common deficit in activity-dependent synapse elimination among different genetic causes of autism |
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exhibits inhibitory roles in cancer cell motility and cell migration |
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adhesion molecule found to protect against tumorigenesis and essential for axonal elongation and actin dynamics during development |
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may influence subcellular actin cytoskeletal organization and axon-axon interactions in the course of familial amyloidotic polyneuropathy |