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FLASH GENE
Symbol PAGE4 contributors: mct/npt - updated : 07-01-2009
HGNC name P antigen family, member 4 (prostate associated)
HGNC id 4108
Location Xp11.23      Physical location : 49.593.905 - 49.598.570
Synonym name
  • G antigen, family C, 1
  • prostate associated gene 4
  • Synonym symbol(s) GAGEC1, PAGE-4, PAGE1, GAGE9, JM27, FLJ35184
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 4.66 kb     5 Exon(s)
    regulatory sequence
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 493 - 102 - Ross (2005)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemoviduct   
     female systemuterus   
     female systemplacenta   
     female systemovary   
     male systemtestis   
     male systemprostate   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    intraspecies homolog to a family of MAGE/GAGE-like proteins
    Homologene
    FAMILY
  • GAGE (G antigen) family
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • multi-functional cytokine that plays a fundamental role during embryonic development
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in prostate, testicular and uterine cancers
    tumoral     --over  
    in benign prostatic hyperplasia
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target represents a promising target for therapeutic intervention of benign prostatic hyperplasia and prostate cancer
    ANIMAL & CELL MODELS