Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol OSBPL7 contributors: mct - updated : 09-02-2013
HGNC name oxysterol binding protein-like 7
HGNC id 16387
Location 17q21.32      Physical location : 45.884.732 - 45.899.147
Synonym name
  • OSBP-related protein 7
  • oxysterol-binding protein-related protein 7
  • Synonym symbol(s) ORP7, MGC71150
    DNA
    TYPE functioning gene
    STRUCTURE 14.41 kb     23 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    23 - 3674 - 842 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestine   highly
    Nervousbraindiencephalonepithalamuspineal gland 
     brainbasal nuclei   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N terminal pleckstrin homology PH domain
  • a highly conserved OSBP-type sterol binding domain in the C terminus
  • HOMOLOGY
    Homologene
    FAMILY oxysterol binding protein family
    CATEGORY receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • may be involved in protein-protein and protein-lipid interactions
  • putative role in communication between the ER and the plasma membrane
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction partner of OSBPL7, GABARAPL2 which regulates Golgi SNARE of 28kDa (GS28) function and stability, and plays a role in autophagosome biogenesis
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS