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FLASH GENE
Symbol NPY5R contributors: mct - updated : 03-05-2014
HGNC name neuropeptide Y receptor Y5
HGNC id 7958
Location 4q31-q32      Physical location : 164.265.090 - 164.273.084
Synonym symbol(s) Y5R
DNA
TYPE functioning gene
SPECIAL FEATURE
text overlapping NPY1R, in opposite orientation
STRUCTURE 8.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Physical map
LOC92345 4q32.2 hypothetical protein BC008207 LOC133332 4q32.2 mitochondrial ribosomal protein S5 pseudogene NPY1R 4q31.3-q32 neuropeptide Y receptor Y1 NPY5R 4q31-q32 neuropeptide Y receptor Y5 DKFZP434L1717 4q32.2 hypothetical protein DKFZp434L1717 FLJ11184 4q32.2 hypothetical protein FLJ11184 FLJ20668 4q32.2 hypothetical protein FLJ20668 ANP32C 4q32.2 acidic (leucine-rich) nuclear phosphoprotein 32 family, member C LOC389239 4 similar to ring finger protein 129 LOC391709 4 similar to 60S ribosomal protein L26 LOC391710 4 similar to ring finger protein 129 LOC389240 4 similar to alpha NAC/1.9.2. protein LOC391711 4 similar to ring finger protein 129 FLJ31659 4q32.3 hypothetical protein FLJ31659 LOC391712 4 similar to ring finger protein 129 LOC391713 4 similar to ring finger protein 129 RNF129 4q32.3 ring finger protein 129
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor, with a deletion in the sixth TM domain
HOMOLOGY
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • may be playing a role in the control of feeding behavior
  • involved in the regulation and development of diet-induced obesity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS nervous system
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction with NPY (induces migration, proliferation, and tube formation of endothelial cells)
  • interaction between NPY1R and NPY5R in the regulation of energy homeostasis
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS