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FLASH GENE
Symbol NPY5R contributors: mct - updated : 03-05-2014
HGNC name neuropeptide Y receptor Y5
HGNC id 7958
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor, with a deletion in the sixth TM domain
HOMOLOGY
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • may be playing a role in the control of feeding behavior
  • involved in the regulation and development of diet-induced obesity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS nervous system
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interaction with NPY (induces migration, proliferation, and tube formation of endothelial cells)
  • interaction between NPY1R and NPY5R in the regulation of energy homeostasis
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS