Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | MZF1 | contributors: mct/npt - updated : 17-12-2015 |
HGNC name | myeloid zinc finger 1 |
HGNC id | 13108 |
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Location | 19q13.43 Physical location : 59.073.284 - 59.084.942 |
Synonym name | |
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Synonym symbol(s) | MZF1B, ZNF42, ZSCAN6, Zfp98, MZF-1B |
DNA |
TYPE | functioning gene |
STRUCTURE | 12.52 kb 6 Exon(s) |
MAPPING | cloned | Y | linked | status | confirmed |
Map | cen - CALM3 - D19S241E - SULT2A1 - LIG1 LIG1 - DBP - LHB LHB - SNRP70 - HRC - CD37 - RRAS - KLK1 - SIGLEC6 - ETFB ETFB - LIM2 - PRKCG /IL11 - SYT3 - FPR1 - ZFP40 - ZNF160 - ZNF134 - ZNF132 - MZF1 - qter |
Authors | Stubbs (96) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage | hemaopoietic (myeloid) cell lineage |
cell lines
fluid/secretion
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at STAGE |
physiological period | fetal |
Text | liver |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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secondary structure | each monomer consists of five alpha helices in two subdomains connected by the alpha2-alpha3 loop |
conjugated | MetalloP |
mono polymer | dimer |
HOMOLOGY |
Homologene |
FAMILY | |
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CATEGORY | transcription factor , protooncogene |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,nucleus,chromatin/chromosome |
basic FUNCTION | |
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CELLULAR PROCESS
| cell life, proliferation/growth |
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nucleotide, transcription, regulation |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | |
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INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
induced by | retinoic acid |
Other | modified by SUMOylation, which provides further support for localization of MZF1 protein complexes to PML-NBs (Noll 2008) |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |