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FLASH GENE
Symbol KIF15 contributors: - updated : 05-06-2006
HGNC name kinesin family member 15
HGNC id 17273
Location 3p21.33      Physical location : 44.803.208 - 44.894.746
Synonym name
  • kinesin-like 7
  • kinesin-like protein 2
  • Synonym symbol(s) HKLP2, KNSL7, NY-BR-62, FLJ25667
    DNA
    TYPE functioning gene
    STRUCTURE 91.00 kb     35 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
     salivary gland    
    Hearing/Equilibriumearinnercochlea  
    Nervousbrain    
     nervecranial nerve   
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one myosin tail
  • a kinesin motor domain
  • HOMOLOGY
    interspecies homolog to murine Kif15 (86.2pc)
    homolog to rattus Kif15 (85.2pc)
    Homologene
    FAMILY kinesin-like protein family
    CATEGORY motor/contractile , DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    basic FUNCTION may be involved in control of cell proliferation
    CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    text control of cell proliferation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein MKI67 (for the progression of mitosis)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS